[Nature Nanotechnology] The authors discovered the ability of the endothelial cell caveolae pumping system to outpace scavenging and deliver nanoparticles rapidly and specifically into the lungs.

[Science Translational Medicine] The authors analyzed airway and peripheral blood immune cells from pediatric patients infected with respiratory syncytial virus (RSV) requiring hospitalization.

[Acta Pharmacologica Sinica] Scientists identified a series of tetrahydro-β-carboline derivatives that effectively reduced the protein expression of Krüppel-like factor 5 (KLF5) and exhibited strong antitumour activity.

[Cancer Immunology Research] The authors investigated the impact of complement factor H (FH) on Tregs within the glioma microenvironment and found that FH is an ICOS ligand.

[Proceedings of The National Academy of Sciences of The United States of America] By comparing gene expression changes at attachment in three marsupial species, the tammar wallaby, opossum, and fat-tailed dunnart, researchers showed that inflammatory attachment was an ancestral feature of marsupial implantation.

[Advanced Materials] By recapitulating the dynamic processes of acute infection, a bioadhesive immune niche domain was developed that facilitated the delivery of timely-activating conjugated nanovaccine (t-CNV) in a metronomic-like manner and increased the accumulation and retention of TANNylated t-CNV in lymph node.

[Advanced Materials] Scientists presented a newly synthesized and screened manganese porphyrins for Mn2+ transport, referred to as photo-STING agonists, and further encapsulate them into core-shell nanoparticles named Rm@PP-GA with dual specificity for tumor tissue and tumor-associated macrophages.

[American Journal of Clinical Oncology-Cancer Clinical Trials] The RAMOSE trial was a randomized, open-label multicenter Phase II study comparing osimertinib with ramucirumab to osimertinib for initial treatment of metastatic EGFR-mutant NSCLC with 2:1 random assignment.

[The Guardian] The UK government will provide funding for a £120 blood test that has the potential to detect the 12 most common forms of cancer before symptoms develop.

[LUNGevity Foundation (PR Newswire)] LUNGevity Foundation, the nation's leading lung cancer-focused nonprofit organization, announced the recipients of their 2024 Career Development Awards.

[Proceedings of The National Academy of Sciences of The United States of America] Using an immunocompetent autologous breast cancer model, the authors investigated a MAtrix REgulating MOtif-mimicking peptide, which inhibited the protumorigenic ECM molecule tenascin-C that activated several cancer hallmarks.

[Regenity Biosciences (BioSpace)] Regenity Biosciences announced that it has received FDA 510(k) clearance to market RejuvaKnee, a minimally invasive collagen-based meniscal implant indicated for use in the reinforcement and repair of soft tissue injuries of the meniscus.