FKBP5 Regulates Osteogenesis of Human iPSC-Derived Mesenchymal Stem Cells via FKBP5-AKT-FOXO1 Pathway

Investigators revealed that FKBP5 promotes the osteogenic differentiation of induced pluripotent stem cell-derived MSCs (iMSCs) partially through the FKBP5-AKT-FOXO1 pathway, presenting a promising approach to iMSC transplantation for clinical bone defects.