Emily Salmini

[Nature Communications] Scientists demonstrated that microglia established direct contact with myelinated axons at Nodes of Ranvier in the spinal cord of mice. The contact associated with neuronal activity occured in a random scanning pattern.

[Brain] Investigators characterized the transcriptional diversity of distinct NEUN+ populations in the human ventral midbrain and then tested for schizophrenia-associated changes in neuronal subset proportions and gene activity changes within neuronal subsets.

[Molecular Psychiatry] Scientists reported that chronic cannabidiol administration significantly mitigated cognitive deficiency and hippocampal β-amyloid pathology in mouse model of Alzheimer’s disease.

[Autophagy] Researchers focused on the lysosomal clustering around the microtubule-organizing center that could regulate the process of autophagosome-lysosome fusion, the final step of autophagy, and examined how lysosomal clustering affects protein degradation through autophagy.

[Acta Biomaterialia] The authors explore the therapeutic potential of glia in transplantation with an emphasis on novel bioengineered tools for enhancement of their reparative properties.

[Nature Medicine] With all the remarkable new approaches to treat neurological disorders, the authors take a critical look at the state of current clinical trials and how challenges may be overcome with the evolving technology and innovation occurring in the stem cell field.