lbeveridge

[Human Cell] The authors elucidated the role of Aplnr signaling during mesoderm cell migration and differentiation from mouse embryonic stem cells.

[Journal Of Periodontal Research] The authors evaluated the effects of β-catenin deletion in Axin2+ cells on cementogenesis. They generated triple transgenic mice to conditionally delete β-catenin in Axin2-lineage cells by crossing Axin2CreERT2/+; R26RtdTomato/+ mice with β-cateninflox/flox mice.

[Stemedica Cell Technologies] Stemedica Cell Technologies announced that it has initiated its “Phase IIb/III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study To Assess The Efficacy, Safety, And Tolerability Of A Single Intravenous Injection Of Allogeneic Mesenchymal Stem Cells To Subjects With Ischemic Stroke”” under an existing US IND using its ischemic tolerant MSC product.

[Bone Research] Investigators comprehensively review the deregulated miRNAs and impaired cellular functions in RA to shed light on several aspects of rheumatoid arthritis pathogenesis, with a focus on excessive inflammation, synovial hyperplasia and progressive joint damage.

[Cell Reports Medicine] Researchers generated 214 cancer organoids from 107 patients, of which 212 are lung cancer organoids , primarily derived from malignant serous effusions.

[Stem Cell Reports] Scientists showed in vivo that deletion of Usp7 in Apc-truncated mice inhibits crypt hyperproliferation and intestinal tumor development.