Noshin Noorjahan

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Ficolin-1 Ameliorates Pulmonary Fibrosis via Directly Binding to TGF-β1

[Journal of Translational Medicine] The expression of ficolin-1 in the plasma of idiopathic pulmonary fibrosis and connective tissue disease- interstitial lung disease patients was first determined.

Newsletters

Impact of Fluid Balance on the Development of Lung Injury

[American Journal of Respiratory and Critical Care Medicine] Thirty-nine healthy female pigs, divided into four groups, were ventilated for 48 hours with high or low mechanical power; and high or low targeted fluid balance.

Newsletters

The Role of PM2.5 Exposure in Lung Cancer: Mechanisms, Genetic Factors, and Clinical Implications

[EMBO Molecular Medicine] The authors summarize the current understanding of how exposure to PM2.5 induces lung carcinogenesis and accelerates lung cancer development.

Neural Cell News

Morphoregulatory ADD3 Underlies Glioblastoma Growth and Formation of Tumor–Tumor Connections

[Life Science Alliance] The authors identified glioblastoma stem cell (GSC) morphology as a new layer of tumoral heterogeneity with important consequences on GSC proliferation.

Neural Cell News

α-Synuclein Pathology as a Target in Neurodegenerative Diseases

[Nature Reviews Neurology] The authors provide a comprehensive overview of pivotal advances in α-synuclein research. They examine structural features and physiological functions of α-synuclein and summarize current insights into key post-translational modifications.

Neural Cell News

The Neurobiology of Thirst and Salt Appetite

[Neuron] Scientists discuss the neural mechanisms that drive animals to seek out and consume water and salt.

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Atorvastatin Calcium Alleviates UVB-Induced HaCat Cell Senescence and Skin Photoaging

[Scientific Reports] Through in vitro experiments with human immortalized keratinocytes (HaCat), researchers found that atorvastatin calcium could significantly reduce the ultraviolet radiation B-induced increased expression of age-related protein p16 and age-related gene p21, and also reduce the up-regulation of inflammatory factors such as IL-1 and IL-6.

Dysregulation in Keratinocytes Drives Systemic Lupus Erythematosus Onset

[Cellular & Molecular Immunology] Investigators found that the level of peroxisome proliferator-activated receptor gamma was substantially reduced in the skin lesions of patients, and replicating this reduction in mice led to rapid disease onset with multiple hallmarks of systemic lupus erythematosus.

USP19 Potentiates Autophagic Cell Death via Inhibiting mTOR Pathway through Deubiquitinating NEK9 in Pancreatic Cancer

[Cell Death & Differentiation] Scientists identified that ubiquitin-specific protease 19 (USP19) was downregulated in pancreatic tumor tissues and forced expression of USP19 diminished tumorigenicity of pancreatic cancer.

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Noshin Noorjahan

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