Cancer Stem Cell News

Cancer Stem Cell News is an online resource that curates the top research publications and reviews about cancer progenitor cells and cancer stem cells.

Propanc Biopharma Receives Notice of Allowance for Proenzyme Compositions to Treat Cancer from the European Patent Office

[Business Wire] Propanc Biopharma, Inc. today announced that a Notice of Allowance has been received from the European Patent Office for claims involving compositions of proenzymes to treat cancer.

Pioneering Engineer-Researcher to Receive 2022 Szent-Györgyi Prize for Progress in Cancer Research

[National Foundation for Cancer Research] The National Foundation for Cancer Research (NFCR) announced today that Dr. Rakesh K. Jain has been selected to receive the 2022 Szent-Györgyi Prize for Progress in Cancer Research.

Histone Lysine Demethylase Inhibition Reprograms Prostate Cancer Metabolism and Mechanics

[Molecular Metabolism] We investigated LSD1/UTX inhibition, two KDMs, in prostate cancer (PCa) and castration-resistant (CRPC) using a multi-omics approach.

Cancer Stem Cell Derived Extracellular Vesicles with Self-Functionalized 3D Nanosensor for Real-Time Cancer Diagnosis: Eliminating the Roadblocks in Liquid Biopsy

[ACS Nano] Investigators reported nanoengineered 3D sensors of extremely small nano-scaled probes self-functionalized for SERS, enabling integrative molecular and functional profiling of otherwise undetectable CSC extracllular vesicles.

The Dual Action of Glioma-Derived Exosomes on Neuronal Activity: Synchronization and Disruption of Synchrony

[Cell Death & Disease] Researchers used an in vitro model to investigate the role of exosomes released by glioma cell lines and by patient-derived glioma stem cells.

Acidosis Induces RIPK1-Dependent Death of Glioblastoma Stem Cells via Acid-Sensing Ion Channel 1a

[Cell Death & Disease] The authors used a tumorsphere formation assay to show that slight acidosis induced necrotic cell death in a manner that was sensitive to the necroptosis inhibitor Nec-1 and to the ASIC1a antagonist PcTx1.

Dicer-Mediated miR-200b Expression Contributes to Cell Migratory/Invasive Abilities and Cancer Stem Cells Properties of Breast Cancer Cells

[Aging-Us] The authors established highly invasive cell lines and observed that Dicer expression was conspicuously lower in the highly invasive cells than in the parental cells.

Primary Cilia and SHH Signaling Impairments in Human and Mouse Models of Parkinson’s Disease

[Nature Communications] Scientists observed a shortening of prostate cancer (PC). Scientists detected a shortening of PC in PINK1-deficient human cellular and mouse models of familial Parkinson’s disease.

A Promising Antitumor Method: Targeting CSC with Immune Cells Modified with CAR

[Frontiers in Immunology] Investigators summarize the recent CSC targets used for CSC inhibition and the different immune effector cells which are engineered with CAR used for CSC therapy.

USP21 Promotes Self-Renewal and Tumorigenicity of Mesenchymal Glioblastoma Stem Cells by Deubiquitinating and Stabilizing FOXD1

[Cell Death & Differentiation] The authors identified the ubiquitin-specific peptidase 21 as a critical FOXD1 deubiquitinase in mesenchymal properties of glioblastoma stem cells.

Griffith Launches Two Cancer Research Centres with $4.6M ACRF Funding

[Griffith University] Griffith University has launched two cancer research centres backed by $4.6 million in funding from the Australian Cancer Research Foundation (ACRF) this month.

Circulating Tumor DNA as a Biomarker for Monitoring Patients with Solid Cancers: Comparison with Standard Protein Biomarkers

[Clinical Chemistry] Following curative-intent surgery for cancer, the presence of ctDNA was highly predictive of early disease recurrence, while in metastatic cancer an early decline in ctDNA following the initiation of treatment is predictive of good outcome.

Cancer Stem Cell News consolidates the most recent publications covering research areas such as the identification and isolation of cancer stem cells, their proliferation and differentiation characteristics, gene expression and regulatory pathways, and the development of anti-cancer therapies. We also include cancer stem cell jobs and events hosted by leading research organizations, societies, and institutes.

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