The authors identified homeobox B9 (HOXB9) as a critical regulator of metastatic metastatic prostate CSCs behavior.
[British Journal of Cancer]
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Scientists investigated the regulatory role of exosomal miR-944 derived from glioma stem cells in glioma progression and angiogenesis.
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Researchers established a niche for glioblastoma stem-like cell selection as a platform and facilitate the assessment of differentiation therapy on glioblastoma multiforme cancer stem-like colonies by retinoic acid with temozolomide-loaded gold nanoparticles associated with low-intensity ultrasound.
[ACS Applied Materials & Interfaces]
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Long non-coding RNAs and miRs are differentially expressed in ovarian cancer (OC) cells and influence OC progression. Investigators explored the underlying roles of LINC00115 and miR-30a in OC.
[Cancer Cell International]
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Scientists describe cancer-initiating cells’ (CICs) contribution to cancer progression.
[Stem Cell Reviews and Reports]
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Investigators reported that the secretory extracellular matrix protein-1 isoform induced tumorigenesis through the GPR motif binding to integrin αXβ2 and the activation of AKT/FAK/Rho/cytoskeleton signaling.
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The roles of small extracellular vesicles (sEVs) from cancer-associated fibroblasts on breast cancer stem cell properties are largely unraveled. Investigators explored the roles of sEVs from cancer-associated fibroblasts on breast cancer progression.
[Cell Death Discovery]
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Researchers demonstrated that 3-HAA sensitized hepatocellular carcinoma cells to sorafenib by reducing tumor stemness.
[Cell Death Discovery]
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Investigators profiled CSC-related long non-coding RNAs (lncRNAs) between radioresistant and parental medulloblastoma cells. The roles of the lncRNA RBM5-AS1 in the stemness and radiosensitivity of medulloblastoma cells were investigated.
[Acta Neuropathologica Communications]
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To determine the immune-modulatory influence of CSC in small cell lung cancer (SCLC), scientists focused on the characterization of CD44+CD90+ CSC-like subpopulations in SCLC.
[Cancer Immunology, Immunotherapy]
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Scientists showed that fibroblast growth factor receptor 2 (FGFR2), particularly the IIIb isoform, was highly expressed in non-CSCs.
[Cancer Biology & Therapy]
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