Nurix Therapeutics Announces Formation of DeCART Therapeutics to Advance New CAR T Therapies Using Targeted Protein Modulation

Nurix Therapeutics, Inc. announced the formation of a new adoptive cell therapy company, DeCART Therapeutics, which has been initially formed as a wholly owned subsidiary of Nurix.
[Nurix Therapeutics, Inc.]
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NeoImmuneTech Announces First Patient Dosed in Phase Ib/IIa Study of NT-I7 (Efineptakin Alfa) and KEYTRUDA® (Pembrolizumab) in Patients with Relapsed/Refractory Advanced Solid Tumors

NeoImmuneTech, Inc. announced the first patient has been dosed at The University of Texas MD Anderson Cancer Center in the Phase Ib/IIa clinical trial of NT-I7 in combination with KEYTRUDA®, a leading checkpoint inhibitor, for the treatment of patients with relapsed/refractory advanced solid tumors.
[NeoImmuneTech, Inc.]
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NIH’s New Sexual-Harassment Rules Are Still Too Weak, Say Critics

On 24 June, the US National Institutes of Health (NIH) described the actions it will take when alerted to reports of unsafe behavior, including restricting scientists from peer-review panels, holding back pending grants and refusing university requests to transfer funding to other institutions in cases where a harasser changes jobs.
[Nature News]
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Gender Gap in Research Output Widens during Pandemic

A series of recent studies has demonstrated a significant drop in the productivity of female scientists, especially those early in their careers, relative to their male peers—and the gender gap is particularly pronounced for COVID-19 researchers.
[The Scientist]
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Graduate Programs Drop GRE after Online Version Raises Concerns about Fairness

Scores of academics have raised concerns about the equity of the online version of the test, arguing it disadvantages prospective students from rural and low-income backgrounds. “If I were … a student trying to take this exam, satisfying [the online testing] criteria would be extremely difficult for me,” says Emily Levesque, an assistant professor of astronomy at the University of Washington, Seattle.
[ScienceInsider]
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Emerging Routes to the Generation of Functional β-Cells for Diabetes Mellitus Cell Therapy

Substantial advances have been made in producing mature β-cells from human pluripotent stem cells that respond appropriately to dynamic changes in glucose concentrations in vitro and rapidly function in vivo following transplantation in mice.
[Nature Reviews Endocrinology]
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Advances and Potential Pitfalls of Oncolytic Viruses Expressing Immunomodulatory Transgene Therapy for Malignant Gliomas

Scientists summarize the research advances related to oncolytic viruses that express immunomodulatory transgenes, as well as potential treatment pitfalls in patients with malignant gliomas.
[Cell Death & Disease]
Zhang, Q., & Liu, F. (2020). Advances and potential pitfalls of oncolytic viruses expressing immunomodulatory transgene therapy for malignant gliomas. Cell Death & Disease, 11(6), 1–11. https://doi.org/10.1038/s41419-020-2696-5 Cite
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COVID-19 Cancels Charity Galas and Walks. Science Is Paying the Price

Foundations that fund biomedical research in the United States, the United Kingdom, and elsewhere are reporting record revenue drops because of the pandemic. One major factor: It has forced them to cancel key fundraising events, including glitzy galas, sponsored walks, Broadway partnerships, and more.
[ScienceInsider]
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Oncolytic Virus-Derived Type I Interferon Restricts CAR T Cell Therapy

Investigators tested whether the inflammatory nature of oncolytic viruses and their ability to remodel the tumor microenvironment may help to recruit and potentiate the functionality of CAR T cells.
[Nature Communications]
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Virtual Lab Tours for Recruitment and Outreach

Virtual lab tours are not new, but they have never been as common as in-person lab tours. However, the pandemic has generated strong incentives for formerly in-person lab tours to go online.
[The Scientist]
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Trump to Suspend New Visas for Foreign Scholars

With a proclamation issued on Monday, US President Donald Trump extended and expanded immigration restrictions to limit the entry of foreign workers to the United States. The move set off ripples of alarm among scientists and drew fire from experts concerned about the future of US science.
[Nature News]
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