Static Magnetic Field–Enhanced Osteogenic Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells via Matrix Vesicle Secretion

Wharton’s jelly mesenchymal stem cells were treated with a 0.4-T static magnetic field. The cell viability was tested using the MTT assay.
[International Journal of Radiation Biology]
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Metabolism of Immune Cells in Cancer

Through the successes of checkpoint blockade and adoptive cellular therapy, immunotherapy has become an established treatment modality for cancer.
[Nature Reviews Cancer]
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Pathomechanisms in Schwannoma Development and Progression

The authors provide an overview of intra- and intercellular mechanisms contributing to schwannoma formation.
[Oncogene]
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Esophageal Extracellular Matrix Hydrogel Mitigates Metaplastic Change in a Dog Model of Barrett’s Esophagus

Dogs with Barrett’s esophagus were treated orally with esophageal mucosa ECM (eECM) hydrogel and omeprazole or omeprazole alone for 30 days. eECM treatment resolved esophagitis, reverted metaplasia to a normal, squamous epithelium in four of six animals.
[Science Advances]
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Cell Derived Matrix Fibulin-1 Associates with Epidermal Growth Factor Receptor to Inhibit Its Activation, Localization and Function in Lung Cancer Calu-1 Cells

To test the possible role Fibulin-1 isoforms could have in regulating Epidermal Growth Factor Receptor signaling and function in lung cancer, scientists performed siRNA mediated knockdown of FBLN1C and FBLN1D in non-small cell lung cancer Calu-1 cells.
[Frontiers in Cell and Developmental Biology]
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Stretchable Active-Matrix Organic Light-Emitting Electrochemical Cell Array

The authors showed for the first time a fully stretchable active-matrix-driven organic light-emitting electrochemical cell array.
[Nature Communications]
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United Kingdom Plans ‘Office for Talent’ to Smooth Entry for Top Scientists

The UK government plans to set up an “office for talent” to oversee visas and make it easier to attract top scientists after Brexit, according to an R&D road map.
[ScienceInsider]
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Hong Kong Universities Rattled by New Security Law

Academics in Hong Kong are facing new worries today after the mainland government abruptly imposed a controversial new security law that critics say could infringe on human rights and chill academic freedom.
[ScienceInsider]
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Amidst Uncertainty, Flexibility Is Key in Higher Ed, Faculty Say

Life sciences professors and other staff make contingency plans for more coronavirus-related disruptions in the coming school year.
[The Scientist]
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A Tissue-Engineered Uterus Supports Live Births in Rabbits

Scientists used biodegradable polymer scaffolds seeded with autologous cells to restore uterine structure and function in rabbits. Rabbits underwent a subtotal uterine excision and were reconstructed with autologous cell-seeded constructs, with nonseeded scaffolds or by suturing.
[Nature Biotechnology]
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Control of Fibroblast Shape in Sequentially Formed 3D Hybrid Hydrogels Regulates Cellular Responses to Microenvironmental Cues

Investigators presented a hydrogel-based platform to control cell shape in three dimensions by using sequentially formed hybrid hydrogels consisting of collagen and alginate.
[NPG Asia Materials]
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