CX3CL1 Homo-Oligomerization Drives Cell-to-Cell Adherence

The analysis of CX3CL1 clusters using native electrophoresis and single molecule fluorescence kinetics showed that CX3CL1 was a homo-oligomer of 3 to 7 monomers. Fluorescence recovery after photobleaching assays revealed that the CX3CL1-transmembrane domain peptide self-associated in both cellular and acellular lipid environments, while its random counterpart did not.
[Scientific Reports]
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City of Hope Signs Licensing Agreement with Scopus BioPharma Inc. to Develop Novel, Targeted Immuno-Oncology Gene Therapy

City of Hope have signed an exclusive, worldwide licensing agreement with Scopus BioPharma Inc. Scopus will further develop and plans to commercialize a City of Hope first-in-class, targeted immuno-oncology gene therapy.
[City of Hope]
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