Top US Health Officials Say They Were Never Told to Slow Down COVID-19 Testing, Contradicting Trump

Four key government health care officials said Tuesday that despite recent remarks from President Trump, they were never ordered to “slow down” diagnostic testing for Covid-19.
[STAT News]
Press Release
Bookmark

No account yet? Register

0
Share

Trump to Suspend New Visas for Foreign Scholars

With a proclamation issued on Monday, US President Donald Trump extended and expanded immigration restrictions to limit the entry of foreign workers to the United States. The move set off ripples of alarm among scientists and drew fire from experts concerned about the future of US science.
[Nature News]
Press Release
Bookmark

No account yet? Register

0
Share

It’s a Nightmare.’ How Brazilian Scientists Became Ensnared in Chloroquine Politics

In April, a published study showed chloroquine could increase mortality in COVID-19 patients. Since then, they have been accused of poisoning their patients with a high dose of chloroquine just to give the drug—praised by US President Donald Trump and his Brazilian counterpart Jair Bolsonaro—a bad name.
[ScienceInsider]
Press Release
Bookmark

No account yet? Register

0
Share

Drug Recently Shown to Reduce Coronavirus Death Risk Could Run Out, Experts Warn

A report that dexamethasone, a commonly used corticosteroid, reduces death rates of COVID-19 by up to one-third was greeted with enthusiasm around the globe. It also raised a question: Will there be enough of the medication?
[ScienceInsider]
Press Release
Bookmark

No account yet? Register

0
Share

Coronavirus Misinformation, and How Scientists Can Help to Fight It

Scientists are well placed to help to hold back the tide of COVID-19 misinformation — but should they get involved in time-consuming, and sometimes bruising, efforts to do so, or just stick to doing good research?
[Nature News]
Press Release
Bookmark

No account yet? Register

0
Share

Human MAIT Cell Cytolytic Effector Proteins Synergize to Overcome Carbapenem Resistance in Escherichia coli

Scientists showed that mucosa-associated invariant T (MAIT) cells mediate MR1-restricted antimicrobial activity against Escherichia coli clinical strains in a manner dependent on the activity of cytolytic proteins but independent of production of pro-inflammatory cytokines or induction of apoptosis in infected cells.
[PLoS Biology]
Full Article
Bookmark

No account yet? Register

0
Share

Restoring Glucose Uptake Rescues Neutrophil Dysfunction and Protects against Systemic Fungal Infection in Mouse Models of Kidney Disease

Researchers showed in multiple models that uremic mice exhibited an increased susceptibility to systemic fungal infection. Uremia inhibited Glut1-mediated uptake of glucose in neutrophils by causing aberrant activation of GSK3β, resulting in reduced ROS generation and hence impaired killing of C. albicans in mice.
[Science Translational Medicine]
Abstract
Bookmark

No account yet? Register

0
Share

Clinical and Immunological Assessment of Asymptomatic SARS-CoV-2 Infections

Researchers studied 37 asymptomatic individuals in the Wanzhou District who were diagnosed with RT–PCR-confirmed SARS-CoV-2 infections but without any relevant clinical symptoms in the preceding 14 days and during hospitalization.
[Nature Medicine]
Full Article
Bookmark

No account yet? Register

0
Share

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

Researchers found that the monoclonal antibody CR3022 bound the receptor binding domain (RBD) tightly, neutralizing SARS-CoV-2 and report the crystal structure at 2.4 Å of the Fab/RBD complex.
[Cell Host & Microbe]
AbstractFull ArticleGraphical Abstract
Bookmark

No account yet? Register

0
Share

COVID-19 Revisiting Inflammatory Pathways of Arthritis

The pattern of pro-inflammatory cytokines induced in COVID-19 has similarities to those targeted in the treatment of rheumatoid arthritis. Several clinical studies are underway that test the effects of inhibiting IL-6, IL-1β or TNF or targeting cytokine signaling via Janus kinase inhibition in the treatment of COVID-19.
[Nature Reviews Rheumatology]
Full Article
Bookmark

No account yet? Register

0
Share

Mucosal-Associated Invariant T (MAIT) Cells Provide B-Cell Help in Vaccinated and Subsequently SIV-Infected Rhesus Macaques

Scientists investigated MAIT cell dynamics and function in rhesus macaque blood and bronchoalveolar lavage following mucosal adenovirus-SIV recombinant priming, intramuscular SIV envelope boosting and infection following repeated low-dose intravaginal SIV exposures.
[Scientific Reports]
Full Article
Bookmark

No account yet? Register

0
Share
Share