Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Mesenchymal Cell News
Mesenchymal Cell News is an online resource that delivers updates on the latest research in the mesenchymal stem cell field.
Transcriptomic and Cellular Decoding of Scaffolds-Induced Suture Mesenchyme Regeneration
[International Journal Of Oral Science] Investigators' data elucidated the natural processes without scaffold transplantation and demonstrated how different scaffolds altered in vivo cellular responses.
Mesenchymal Stem Cells Derived-Exosomes Enhanced Amniotic Membrane Extract Promotes Corneal Keratocyte Proliferation
[Biotechnology Progress] The authors evaluated the effects of both amniotic membrane extract and Wharton's jelly MSC derived-exosomes, individually and together, on the proliferation of corneal keratocytes as well as their ability to promote in vitro cell migration, wound healing, and their impact on cellular morphology.
PPARγ Inhibition Promotes Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells and Fracture Healing
[Journal Of Cellular Biochemistry] Bone healing processes in the rat femur fracture model were recorded and assessed by radiographic methods on Weeks 8, 14, and 20 postoperation.
NIH Grant Supports Additional Baby Metabolism Research
[East Carolina University] A five-year, $2.5 million R01 grant from the National Institutes of Health will help East Carolina University faculty members continue research on ways to curb generational obesity.
Mesenchymal Stem Cells as Therapeutic Vehicles for Glioma
[Cancer Gene Therapy] MSCs exhibit advantages for glioma therapy because of their ability to pass through the blood–brain barrier and migrate to tumor cells and their tolerance to the immune system.
Transcriptome and Single-Cell Analysis Reveal Disulfidptosis-Related Modification Patterns of Tumor Microenvironment and Prognosis in Osteosarcoma
[Scientific Reports] Scientists investigated disulfidptosis-related modification patterns in osteosarcoma (OS) and their relationship with survival outcomes in patients with OS.
Mitochondrial Enzyme FAHD1 Reduces ROS in Osteosarcoma
[Scientific Reports] Scientists investigated the impact of overexpressing the mitochondrial enzyme Fumarylacetoacetate hydrolase domain-containing protein 1 (FAHD1) in human osteosarcoma epithelial cells in vitro.
The IL-6 Signaling Pathway Contributes Critically to the Immunomodulatory Mechanism of Human Decidua-Derived Mesenchymal Stromal Cells
[iScience] Researchers found that knock-down IL-6 in decidua-derived MSCs reduced the expression of PD-L1 and PD-L2, which are known as classical immune checkpoint inhibitors.
Ohwia caudata Aqueous Extract Attenuates Senescence in Aging Adipose-Derived Mesenchymal Stem Cells
[Heliyon] Using 0.1 μM doxorubicin, investigators induced aging in human adipose-derived MSCs and evaluated whether various concentrations of O. caudata aqueous extract exhibited anti-aging effects on them.
Inhibition of the Galactosyltransferase C1GALT1 Reduces Osteosarcoma Cell Proliferation by Interfering with Erk Signaling and Cell Cycle Progression
[Cancer Gene Therapy] Researchers screened for differentially expressed genes in osteosarcoma. They found that osteosarcoma cases could be divided into fair and poor survival groups based on gene expression profiles.
POLE2 Promotes Osteosarcoma Progression by Enhancing the Stability of CD44
[Cell Death Discovery] GSE14359 chip from the GEO database was used to screen differentially expressed genes in osteosarcoma (OS). DNA polymerase epsilon 2 (POLE2) was confirmed to overexpress in OS tissues and cell lines by immunohistochemical staining, qPCR, and Western blot.
Effect of In Vivo Culture Conditions on the Proliferation and Differentiation of Rat Adipose-Derived Stromal Cells
[Mechanisms of Ageing and Development] Scientists transplanted separated adipose-derived stromal cells into local subcutaneous adipose tissues of nude mice as an in vivo cell culture model.
Mesenchymal Cell News covers topics such as the isolation, identification, and culturing conditions of mesenchymal stem cells, as well as their cellular characterization, behavior and differentiation capacities. We also include research that focuses on identifying tissue sources of mesenchymal stem cells and their potential therapeutic applications in regenerative medicine and cellular therapies.
