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Vol. 10.43 – 3 November, 2021
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Researchers highlighted that lncROPM and its target PLA2G16 played crucial roles in sustaining breast CSC (BCSC) properties and might serve as a biomarker for BCSCs or other cancer stem cells.
[Journal of Hematology & Oncology]
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PUBLICATIONSRanked by the impact factor of the journal
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Scientists found a set of hormone-responsive lineage-specific transcription factors, FOXA1, GATA3, ERα, directly drove high expression of arylsulfatase D (ARSD) through chromatin looping in luminal subtype breast cancer cells.
[Cell Death & Disease]
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The PERK pathway inhibited global protein synthesis while allowing translation of specific mRNAs, such as the ATF4 transcription factor.
[Cell Death & Disease]
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Researchers demonstrated that KIT was a downstream effector of TCOF1 in mediating triple-negative breast cancer stemness.
[British Journal of Cancer]
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Investigators applied droplet-based single-cell RNA sequencing to acquire transcriptional profiles of 36 619 single cells isolated from seven patients.
[International Journal of Cancer]
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Scientists carried out systematic analyses of metabolites in patient-derived colorectal cancer spheroids, and identified high levels of kynurenine and TDO2 that were positively associated with liver metastasis.
[Cancer Science]
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The authors investigated the role of ASAP1 Intronic Transcript 1 (ASAP1-IT1) in cancer cell stemness of non-small cell lung cancer.
[Cancer Cell International]
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Scientists developed a culture system regulating culture temperature immediately and accurately by employing metallic culture vessels. Michigan Cancer Foundation-7 cells and normal human dermal fibroblasts were used for models of cancer and normal cells.
[Scientific Reports]
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SOX12 plays a role in promoting the growth of some tumors; however, its role in osteosarcoma remains unclear. Researchers performed in vitro and in vivo assays to determine SOX12 function in osteosarcoma etiology.
[Stem Cells International]
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The interaction between cancer cells and platelets was examined in 15 epithelial cell lines, representing 7 cancer types. Gene expression analysis of epithelial mesenchymal transition-associated and cancer stemness genes was performed by RT-PCR.
[Translational Oncology]
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Scientists discuss the integrin signalosome with a highlight of a few key pro-oncogenic pathways elicited by integrins, and uncover the mutational and transcriptomic landscape of integrin-encoding genes across human cancers.
[Journal of Hematology & Oncology]
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The authors review recent literature on energy production in glioblastoma stem cells and leukemic stem cells versus their normal counterparts, neural stem cells and hematopoietic stem cells, respectively.
[Journal of Histochemistry & Cytochemistry]
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Sorrento Therapeutics, Inc. has submitted a NDA for the anti-PD-L1 antibody, socazolimab, licensed from Sorrento to China Oncology Focus, Ltd. for the greater China territory to treat recurrent or metastatic cervical cancer. The NDA application has been accepted by China NMPA.
[Sorrento Therapeutics, Inc.]
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November 15 – 17, 2021
Virtual
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St. Jude Children’s Research Hospital – Memphis, Tennessee, United States
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The University of Texas MD Anderson Cancer Center – Houston, Texas, United States
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Cedars-Sinai Medical Center – Los Angeles, California, United States
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Cancer Research UK Manchester Institute – Manchester, United Kingdom
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University of California Los Angeles – Los Angeles, California, United States
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
Umbilical & Placental Cell News
