 | | Vol. 10.44 – 10 November, 2021 |
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| Immunofluorescence, immunoprecipitation, lectin blot and quantitative real-time PCR were used to investigate the expression of N-acetyl-α-galactosaminyltransferases (GALNT8) and its role in regulating estrogen receptor α via bone morphogenetic protein signaling.
[Biochimica Et Biophysica Acta-General Subjects] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed that the activation of the RON receptor tyrosine kinase signaling pathway specifically in macrophages supports breast cancer growth and metastasis.
[Oncogene] |
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| Investigators engineered a photodynamic nanoplatform to manipulate breast cancer stem cells against tumor progression and metastasis by not only remolding the disequilibrium state but also blocking the epithelial-mesenchymal transition process.
[Journal of Controlled Release] |
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| Researchers identified the cell surface binding partner of Reg4 and dissecting its role in colorectal cancer (CRC) and pancreatic cancer (PC) growth and stem cell survival. In vitro models of human CRC and PC were used to evaluate the results.
[Molecular Cancer Research] |
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| Researchers found that sensitivity toTemozolomide (TMZ) was suppressed by significantly increasing the major vault protein (MVP) expression in glioblastoma multiforme cells with TMZ resistance.
[Translational Oncology] |
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| After integrating the tumor stemness index based on mRNA expression, immune score, mRNA expression, and clinical information from the TCGA database, scientists screened 380 tumor stemness and immune (TSI)-related genes and constructed a five TSI-specific-gene signature.
[Cancer Medicine] |
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| Scientists investigated the expression profile and biological function of lncRNAs in urothelial cancer stem-like cells by microarray analysis.
[Experimental Cell Research] |
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| Scientists explored the differentially expressed miRNAs related to tumor cell-derived extracellular vesciles (EVs) and the mechanism by which EVs regulated hepatoblastoma progression.
[Journal of Immunology Research] |
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| Epithelial cell adhesion molecule+ (EpCAM+), cluster of differentiation 90+ (CD90+) and EpCAM+/CD90+ circulating tumor cells were sorted via fluorescence-activated cell sorting, and transcripts level of EpCAM, K19 and CD90 in the peripheral blood were analyzed via real-time polymerase chain reaction preoperatively.
[Gut and Liver] |
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| The authors address the noncanonical roles of p53 and their implications in sarcoma initiation and progression.
[Cancer Letters] |
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| The authors review how long non-coding RNAs regulate alternative splicing and influence oncogenesis in different ways.
[British Journal of Cancer] |
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| BriaCell Therapeutics Corp. announced the addition of Suzanne Ostrand-Rosenberg, PhD to its Scientific Advisory Board.
[BriaCell Therapeutics Corp. (GlobeNewswire, Inc.)] |
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| November 10 – 19, 2021
Virtual |
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| | Oregon Health & Science University – Portland, Oregon, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| The University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | Cedars-Sinai Medical Center – Los Angeles, California, United States |
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| University of California Los Angeles – Los Angeles, California, United States |
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