| Vol. 11.15 – 20 April, 2022 |
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| Scientists investigated the role of immunoglobulin superfamily member 8 on normal and malignant hematopoietic stem cells, mainly using the conditional knockout model. [Leukemia] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| CSCs were isolated from MIA PaCa-2 and PANC1 human pancreatic cancer cell lines. Titanium peroxide nanoparticles were synthesized from titanium dioxide nanoparticles and utilized as radiosensitizers. [Journal of Experimental & Clinical Cancer Research] |
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| Investigators reported that MEOX2 functioned as a tumor-initiating element in glioma. Bioinformatic analysis of public databases and investigation of MEOX2 expression in patients with glioma demonstrated that MEOX2 was abundant at both mRNA and protein levels in glioma. [Cell Death & Disease] |
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| The authors investigated the current knowledge on circulating tumor DNA and its clinical utility in predicting outcomes in patients with metastatic colorectal cancer. [British Journal of Cancer] |
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| Investigators reported that the voltage-gated calcium channel α2δ1 subunit-positive tumor-initiating cells of hepatocellular carcinoma specifically secreted LOX, which led to the crosslinking of collagen, forming a stiff extracellular matrix. [Carcinogenesis] |
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| Colony formation assay, sphere formation assay, and flow cytometry were used to evaluate glioma stem cell stemness. [Journal of Cellular and Molecular Medicine] |
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| Researchers measured the oxygen enhancement ratio for cell survival after X-ray exposure in normal fibroblast and radioresistant patient-derived glioblastoma stem cells. [Radiation Oncology] |
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| Scientists investigated the effect and mechanism of long noncoding RNA KCNQ1OT1 on pituitary adenoma. The KCNQ1OT1 expression in invasive and noninvasive PA tissues was detected by real-time fluorescence quantitative polymerase chain reaction. [Journal of Oncology] |
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| Researchers showed that formate, a metabolite produced by colorectal cancer (CRC)-associated bacterium Fusobacterium nucleatum, promoted CRC development and that microbiome-derived formate drove CRC tumor invasion by triggering AhR signalling, while increasing cancer stemness. [Nature Metabolism] |
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| Scientists outlined how developments in the cancer field are paving the way for cellular immunotherapeutics in other diseases. [Nature Medicine] |
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| The authors discuss recent advances in understanding the contribution of HDACs to the maintenance of the transformed state and the rational for their selective targeting. [Pharmacology & Therapeutics] |
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| Memorial Sloan Kettering Cancer Center announced the establishment of The Starr Foundation Program for Discovery Science, a pioneering new initiative made possible by a $50 million gift from The Starr Foundation. [Memorial Sloan Kettering Cancer Center (News Wise)] |
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| May 4 – 7, 2022 San Francisco, California, United States |
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| McGill University – Montreal, Quebec, Canada |
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| Cyprus Cancer Research Institute – Nicosia, Cyprus |
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| The University of Hong Kong – Hong Kong, China |
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| Luxembourg Institute of Health – Strassen, Luxembourg |
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| Genentech, Inc. – South San Francisco, California, United States |
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