 | | Vol. 11.25 – 29 June, 2022 |
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| Forced expression of MECOM in lung squamous cell carcinoma cell lines promoted CSC properties, and its knockout inhibited CSC phenotypes.
[Molecular Therapy] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors utilized a co-culture model of bone marrow mesenchymal stem cells and estrogen receptor+ breast cancer cells to recapitulate interactions of cancer cells in bone marrow niches.
[Oncogene] |
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| Researchers used a reference of 14,968 human endogenous retroviruses (HERV) functional units to provide a thorough analysis of HERV expression in normal and acute myeloid leukemia bone marrow cells.
[American Journal of Hematology] |
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| Scientists showed that high TLR2 expression is linked to poor prognosis in breast cancer patients, therefore representing a candidate target for breast cancer treatment.
[Oncoimmunology] |
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| Researchers investigated the effect of garcinone C on cancer stemness and invasiveness in colorectal cancer; Gli1 was noted as pivotal in maintaining stemness and invasiveness in HCT116 and HT29 CSCs.
[Journal of Agricultural and Food Chemistry] |
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| Scientists investigated the role of cancer stem cell-like cells-derived exosomal CDKN2B-AS1 in thyroid cancer and the underlying regulatory mechanism.
[Experimental Cell Research] |
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| CDC20 knockdown did not increase TMZ- and radiation-induced DNA damage, or alter DNA damage repair, but rather promoted cell death through accumulation of the pro-apoptotic protein, Bim.
[PLoS One] |
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| The authors indicated that C-X-C motif chemokine receptor 4 (CXCR4) mediated the upregulation of Kruppel like factor 5, a zinc-finger-containing transcription factor, to facilitate the proliferation of glioma initiating cells.
[Cell Biology International] |
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Researchers identified the antitumourigenic activities of the medicinal compound chelerythrine chloride (CHE) on melanoma CSCs. CHE induced apoptosis in A375 and A2058 CSCs.
[Computational and Mathematical Methods in Medicine] |
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| Investigators discuss whether stem-ness enables metastasis or mutations drive metastasis. They ponder about low-grade versus high-grade tumors and about primary versus metastatic tumors.
[Seminars in Diagnostic Pathology] |
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| Panavance Therapeutics, Inc. announced the US FDA has granted Orphan Drug Designation to GP-2250 for the treatment of all forms of pancreatic cancer.
[Panavance Therapeutics, Inc.] |
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| To increase public understanding of the causes of prostate cancer, the University of Hawaiʻi Cancer Center will lead a $3.5 million public impact research study to further our understanding of prostate cancer to improve prediction of future disease.
[University of Hawai’i News] |
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| October 3 – 4, 2022
San Diego, California, United States |
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| | University Health Network – Toronto, Ontario, Canada |
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| | The Ohio State University Comprehensive Cancer Center – Columbus, Ohio, United States |
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| | University of Bristol – Bristol, England, United Kingdom |
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| | Institute of Cancer Research – London, England, United Kingdom |
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| | Sanford Research – Sioux Falls, South Dakota, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
