 | | Vol. 12.04 – 1 February, 2023 |
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| Researchers characterized the transcriptomes of human pancreatic ductal adenocarcinoma circulating tumor cells, primary, and metastatic lesions at a single-cell scale.
[Cancer Cell] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators unveiled that Glutathione S-transferase pi (GSTP1) was upregulated in lung CSCs and supports tumor self-renewal, metastasis, and resistance to targeted tyrosine kinase inhibitors of lung adenocarcinoma both in vitro and in vivo.
[Advanced Science] |
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| Scientists found that a novel activating mutation of the axon guidance gene PLXNB2 sustained proliferative autonomy and confered invasive properties to stem cells isolated from cancers of unknown primary.
[Embo Molecular Medicine] |
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| Researchers sought to identify the new target that was involved in inflammation-related liver tumorigenesis.
[Journal of Experimental & Clinical Cancer Research] |
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| Epithelial cell adhesion molecule/vimentin/Glypican-3 antibody-modified lipid magnetic spheres were used to capture tumor cells with epithelial phenotype in order to capture more circulating tumor cells with a more comprehensive phenotype for monitoring tumor metastasis.
[Journal of Nanobiotechnology] |
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| Investigators explored biomarkers of tumor stemness (TS) by single-cell sequencing analysis. Subtypes of bladder urothelial carcinoma were identified using clustering analysis based on TS biomarkers.
[Stem Cell Research & Therapy] |
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| The authors delineated the active enhancer landscape and observed pervasive enhancer malfunction in leukemia stem cells.
[Blood Advances] |
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| Researchers selectively isolated and characterized extracellular vesicles from CSC or differentiated cancer cells from the MDA-MB-231 triple negative breast cancer cell line.
[International Journal of Cancer] |
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| In vivo antitumor efficacy showed that the compound nanoemulsion could reduce the proportion of breast cancer stem cells to 1.18% by inhibiting the expression of Pin1.
[Molecular Pharmaceutics] |
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| Investigators evaluated the anticancer activities of 17 novel terpestacin derivatives against U87MG-derived glioblastoma stem cells.
[Bioorganic Chemistry] |
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| The authors discuss leukemic stem cell (LSC) biology and associated resistance mechanisms, potential therapeutic LSC vulnerabilities and current clinical trial activities.
[Haematologica] |
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| Scientists discuss the latest insights into the characteristics, markers, and mechanisms of CSCs and describe the crosstalk between CSCs and other cells in the tumor microenvironment.
[Biochemical Pharmacology] |
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| A panel of experts joined a meeting of the US National Science Advisory Board of Biosecurity, discussing on issues such as how privately funded risky research would be regulated, the role of research institutions in identifying potentially dangerous research, and much more.
[Nature] |
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| April 17 – 19, 2023
Lund, Sweden |
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| | Beckman Research Institute – Monrovia, California, United States |
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| | Essen University Hospital – Essen, Germany |
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| | University of Bergen – Bergen, Norway |
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| | Michigan State University – East Lansing, Michigan, United States |
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| | IRCCS Candiolo Cancer Institute – Turin, Italy |
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Cancer Stem Cell News
Cell Therapy News
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Intestinal Cell News
Mammary Cell News
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Neural Cell News
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Pancreatic Cell News
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