 | | Vol. 12.10 – 15 March, 2023 |
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| Tumor samples from patients with triple-negative breast cancer (TNBC) and non-TNBC revealed that increased numbers of CD56bright natural killer cells were present in TNBC tumors, and were correlated to poor overall survival in patients with TNBC.
[Science Translational Medicine] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists identified a long noncoding RNA, termed PVT1, which was highly expressed in CSCs and correlated closely with lymph node metastasis of head and neck squamous cell carcinoma.
[Cell Death & Disease] |
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| Investigators identified X-inactive specific transcript (XIST) as a key regulator of breast CSCs, which exhibit aldehyde dehydrogenase positive epithelial-and CD24loCD44hi mesenchymal-like phenotypes.
[Oncogene] |
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| To screen drugs to overcome differentiation blockade for acute myeloid leukemia, researchers conducted screening of 2040 small molecules from a library of US FDA-approved drugs and found that the cyclin-dependent kinase 4/6 inhibitor, abemaciclib, exerted high anti-leukemic activity.
[British Journal Of Haematology] |
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| Co-culture systems in vitro and co-implantation systems in vivo were designed to characterize the interactions between breast CSCs and bulk cancer cells.
[Cell Communication and Signaling] |
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| The authors explored the antiangiogenic mechanism of quinacrine-gold hybrid nanoparticle and near-infrared radiation in patient-derived primary breast CSCs.
[Nanomedicine] |
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| WD repeat domain 3 (WDR3) was negatively correlated with USF2, which was degraded by promoting ubiquitination of USF2, and USF2 interacted with promoter region-binding elements of RASSF1A to depress prostate cancer stemness and growth.
[The Journal Of Gene Medicine] |
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| Investigators validated the efficacy of in vivo detection of circulating tumor cells in bladder cancer (BC) patients. A total of 216 BC patients were enrolled in this study.
[Medical Oncology] |
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| The authors uncovered the relationship between cell density and CSCs, and the role of the Warburg effect in regulating CSC-like characteristics.
[Biology Open] |
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| Scientists describe the cutting-edge research undertaken in the field of nanotechnology and material science to develop biomaterials-based platforms as effective immunotherapeutics.
[Acta Biomaterialia] |
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| The 2024 spending plan President Joe Biden unveiled continues his administration’s pattern of asking for large increases at major US research agencies.
[Science Insider] |
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| April 25 – 26, 2023
London, England, United Kingdom |
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| | Dana-Farber Cancer Institute – Boston, Massachusetts, United States |
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| | University of Pennsylvania – Philadelphia, Pennsylvania, United States |
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| | The German Cancer ReÂsearch Center – Heidelberg, Germany |
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| | Stanford University School of Medicine – Stanford, California, United States |
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| | University of British Columbia – Vancouver, British Columbia, Canada |
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Cancer Stem Cell News
Cell Therapy News
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Intestinal Cell News
Mammary Cell News
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Neural Cell News
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