 | | Vol. 13.20 – 21 August, 2024 |
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| Researchers used a mouse model and primary tumor cell lines to investigate putative CSC populations. They established peptidoglycan recognition protein 1 as a novel CSC-associated marker crucial for immune evasion.
[Gut] |
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 | | PUBLICATIONSListed by the impact factor of the journal |
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| Data from the large Phase III IMpower150 study of atezolizumab in combination with chemotherapy with or without bevacizumab in patients with stage IV non-squamous Non-Small Cell Lung Cancer suggested that post-treatment circulating tumor DNA response correlated significantly with radiographic response.
[Nature Communications] |
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| Researchers investigated the role of targeted autophagic protein degradation in regulating ovarian CSC fate decisions and chemo-resistance.
[Journal of Experimental & Clinical Cancer Research] |
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| Immunohistochemistry was used to evaluate the expression of M2-like tumor-associated macrophages and CSC markers in 24 pairs of gallbladder cancer and adjacent noncancerous tissues from patients with GBC.
[Experimental Hematology & Oncology] |
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| A highly effective 3D soft fibrin gel system was used to enrich breast cancer stem cells-like cells from ER+ breast cancer lines MCF7 and MDA-MB-415.
[Stem Cell Research & Therapy] |
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| The authors present the Cancer Stemness Online, an integrated resource for efficiently scoring cancer stemness potential at the bulk and single-cell levels. The resource integrates eight robust predictive algorithms as well as 27 signature gene sets associated with cancer stemness for predicting stemness scores.
[Genomics Proteomics & Bioinformatics] |
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| FZD6 promoted high-grade serous ovarian cancer (HGSOC) growth and peritoneal metastasis. It endued HGSOC cells with stem-like properties by modulating POU5F1, ALDH1, and EPCAM. It could also desensitize HGSOC cells to certain chemical drugs.
[Molecular Carcinogenesis] |
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| Researchers investigated the CSC-like properties induced by CD63-BCAR4 fusion gene, previously reported as an oncogenic fusion, and its potential contribution for the enhanced metastasis as a notable characteristic of CD63-BCAR4.
[Molecular Carcinogenesis] |
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| Investigators identified the CHD4 R975H mutation as a high-frequency occurrence in endometrial cancer (EC) patients through a comprehensive survey of EC databases.
[Scientific Reports] |
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| By integrating the latest research findings and clinical evidence, scientists seek to elucidate the pivotal role of receptor tyrosine kinases (RTKs) in cancer biology and the therapeutic efficacy of RTK inhibition with promising treatment outcomes.
[Signal Transduction and Targeted Therapy] |
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| CSCs are able to maintain their stemness by regulating the metabolic networks to maintain their stemness characteristics, enhance antioxidant defences, and adapt to therapeutic stress.
[Frontiers In Cell and Developmental Biology] |
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| President Joe Biden took a break from the Elect Harris campaign trail, to advance policy goals close to his heart – the administration’s “moonshot” initiative to dramatically reduce cancer deaths.
[The Lens] |
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| BioNTech said the FDA has lifted a partial clinical hold on an early-stage study of its experimental cancer drug.
[Reuters] |
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| A Rice University-led multi-institutional research collaboration has won an award of up to $18 million over five years from the Advanced Research Projects Agency for Health to develop and validate a new system for improving tumor removal accuracy for two types of cancer: breast, and head and neck cancer.
[Rice University] |
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| September 30-October 03, 2024
Heidelberg, Germany & Online |
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| | Melanoma Institute Australia – Wollstonecraft, North Sydney, Australia |
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| | BC Provincial Health Services Authority – Vancouver, British Columbia, Canada |
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| | University of Oulu – Oulu, Finland |
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| | St. Anna Children’s Cancer Research Institute – Vienna, Austria |
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| | City of Hope – Monrovia, California, United States |
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