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Tokyo Team Develops Safe Way to Grow iPS Cells
A Japanese team has developed a new method of growing human induced pluripotent stem cells that uses a gel chemical compound instead of animal cells.
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Researcher Seeks to Turn Human Stem Cells Into Blood Vessels
A Johns Hopkins engineer is trying to coax human stem cells to turn into networks of new blood vessels with a $150,000 two-year grant from the March of Dimes Foundation.
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Stem Cell ‘Fabrics’ Promise Universal Tissue
Embryonic stem cells can survive being spun into polymer threads – a technique that could be used to weave flexible synthetic tissues able to adapt to any transplant environment, say UK biophysicists.
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Cell Microenvironments Hold Key to Future Cancer and Regenerative Medicine Therapies
Working with unique microenvironment micro arrays (MEArrays) of their own creation, researchers have shown that the ultimate fate of a stem or progenitor cell in a woman’s breast may depend upon signals from multiple microenvironments.
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Gladstone Scientists Find Clues That Guide Division and Expansion of Heart Cells for Regenerative Therapies
Researchers have unraveled a complex signaling process that reveals how different types of cells interact to create a heart.
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World’s Smallest Periscopes Peer At Cells From Several Sides At Once
A team of Vanderbilt scientists has invented the world’s smallest version of the periscope and is using it to look at cells and other microorganisms from several sides at once.
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Human Stem Cells Provide a New Model for Lou Gehrig’s Disease
Overcoming the limited success of previous models, a report published in Disease Models & Mechanisms describes how neurons can be derived from human stem cells, and engineered to mimic inherited ALS.
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Adipose-Derived Stem and Regenerative Cells Prevent Mortality and Reduce Kidney Damage in Preclinical Study
Cytori Therapeutics, Inc. finds adipose tissue-derived stem and regenerative cells significantly reduce mortality and improve renal function in an acute kidney injury model.
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First Group of Heart Failure Patients Treated with “Off-the-Shelf” Adult Stem Cells Successfully Pass Key Safety Milestone
Mesoblast Limited recently announced successful achievement of the key safety milestone in the first low-dose cohort of patients treated with their adult stem cell product Revascor.
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ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Cells Extract from Fetal Liver Promotes the Hematopoietic Differentiation of Human Embryonic Stem Cells
This paper describes a new inducing system to promote the differentiation of human stem cells toward hematopoietic lineages by the treatment with cells extract of human fetal liver tissue.
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Functional Implications of CD34 Expression in Human Adipose-derived Stem/Progenitor Cells
This study sorted shortly cultured hASCs into CD34+ and CD34– fractions and compared their biological functions to assess the implications of decreased CD34 expression in human adipose-derived stem cells over time in culture.
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ROCK Inhibitor Improves Survival of Cryopreserved Serum/Feeder-free Single Human Embryonic Stem Cells
The researchers describe a novel method to increase freeze-thaw survival and proliferation rate of single hES cells in serum-free and feeder-free culture conditions.
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Human Embryonic Stem Cell-derived Motor Neurons Expressing SOD1 Mutants Exhibit Typical Signs of Motor Neuron Degeneration Linked to ALS
Here, the researchers demonstrate the expression of a mutant gene, superoxide dismutase 1(SOD1), linked to familial amyotrophic lateral sclerosis in hESC-derived motor neurons.
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Ctip2/Bcl11b Controls Ameloblast Formation During Mammalian Odontogenesis
This research describes how Ctip2 also plays a key role in tooth development.
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