Phase II ALS Clinical Trial with BrainStorm Cell Therapeutics’ NurOwn™ to Be Expanded to a Third Premiere U.S. Clinical Site BrainStorm Cell Therapeutics announced that Mayo Clinic in Rochester, Minnesota has entered into a Memorandum of Understanding with the intent to conduct a Phase II clinical trial of NurOwn™ in amyotrophic lateral sclerosis (ALS). [BrainStorm Cell Therapeutics, Inc.] Press Release Potomac Photonics Supports BU’s Stem Cell Research with 3D Printed Parts Digital Manufacturing Leader Potomac Photonics announced that it recently completed precision 3D printed parts for Boston University (BU) to support their research in stem cells. Utilizing a high-resolution 3D printer, Potomac Photonics fabricated precision stencils to pattern seeded stem cells such that cells are grown in a defined arrangement relative to each other. By preparing various stencils, the BU researchers hope to determine how the relative position of stem cells affect their differentiation efficiency and differentiated progeny. [Potomac Photonics] Press Release Sistemic and Leading CDMO, Progenitor Cell Therapy (PCT) Initiate Study on Novel Stem Cell Characterization Technology Sistemic Limited (Sistemic) announced the signature of an agreement to allow Progenitor Cell Therapy (PCT) to initiate evaluation studies on Sistemic’s SistemQC™ stem cell characterization technology. The studies have been designed to allow PCT to evaluate the broad applicability of SistemQC™ technology in stem cell characterization employing Sistemic’s patented miRNA profiling system and proprietary analytical approaches to produce miRNA panels, termed Key miRNAs or KmiRs™, which PCT may look to employ in the future in process optimization and cell characterization. [Sistemic Limited] Press Release NIH Funding Puts Researchers on Path to Restoring Vision Loss from Diabetic Eye Disease Researchers at the Eugene and Marilyn Glick Eye Institute and the Indiana Center for Vascular Biology at Indiana University School of Medicine are on the cusp of perfecting stem cell treatments that would halt, and potentially reverse, vision loss caused by diabetic retinopathy. [Eugene and Marilyn Glick Eye Institute] Press Release Alnylam Initiates Phase I Clinical Study for ALN-TTRsc, a Subcutaneously Administered RNAi Therapeutic Targeting Transthyretin (TTR) for the Treatment of TTR-Mediated Amyloidosis (ATTR) Alnylam Pharmaceuticals, Inc. announced that it has initiated dosing in its Phase I clinical trial with ALN-TTRsc, an RNAi therapeutic targeting TTR for the treatment of ATTR. [Alnylam Pharmaceuticals, Inc.] Press Release ZIOPHARM Oncology Initiates Phase II Study of Ad-RTS IL-12 and Palifosfamide Combination for Treatment of Advanced Breast Cancer ZIOPHARM Oncology, Inc. announced the initiation of a randomized, open label Phase II clinical study of Ad-RTS IL-12 in combination with palifosfamide to treat patients with non-resectable recurrent or metastatic breast cancer. Ad-RTS IL-12 is a targeted and controlled DNA-based therapeutic designed to express interleukin-12 (IL-12), a protein important for an immune response to cancer. [ZIOPHARM Oncology, Inc.] Press Release Immune Therapy from Austria Receives Orphan Drug Designation from European Medicines Agency The European Medicines Agency awarded the Austrian biotech company Activartis an Orphan Drug Designation for its innovative Cancer Immune Therapy AV0113. The Orphan Drug Designation applies specifically to the use of AV0113 for the treatment of glioma, a type of brain tumor, which afflicts around one in 10.000 people in the EU. [Activartis Biotech GmbH] Press Release NeoStem Announces Intellectual Property Expansion in Cardiovascular Disease NeoStem, Inc. announced that Amorcyte, LLC, its wholly owned subsidiary, received a Notice of Allowance of claims from the U.S. Patent and Trademark office for patent application 13/285,606 covering a method of treating a progressive myocardial injury caused by an ischemic condition and utilizing a multi-dosing regimen. Once granted, this will represent Amorcyte’s fourth U.S. patent and sixth patent overall. [NeoStem, Inc.] Press Release Cryo-Cell International Affiliate Earns Patent for Processing Umbilical Cord Blood for Therapeutic Use in Treating Neurodegenerative Diseases and Spinal Cord and Brain Injuries A patent issued to Saneron CCEL Therapeutics, Inc. and the University of South Florida may facilitate increased use of cord blood stem cells in medical therapies, according to Linda Kelley, Ph.D., chief scientific officer with Cryo-Cell International. The patent was awarded for a method of retrieval, incubation and transplantation of cells derived from umbilical cord blood. [Cryo-Cell International, Inc.] Press Release Launch of the Chinese-German Center for Bio-Inspired Materials at the Mainz University Medical Center A German research team led by Professor Dr. Werner E. G. Müller of the Institute of Physiological Chemistry at the University Medical Center of Johannes Gutenberg University Mainz and scientists from the Chinese Academy of Sciences and the Chinese Academy of Geological Sciences have launched a Chinese-German Joint Center for Bio-Inspired Materials. Here, the researchers will be able to work closely together on projects in the field of regenerative medicine. [Johannes Gutenberg-Universität Mainz] Press Release |