BioNTech and Genmab Sign Co-Development and Commercialization Agreement in Immuno-Oncology BioNTech AG announced that it has signed an agreement with Genmab A/S to jointly research, develop and commercialize multiple bispecific antibodies for cancer immunotherapy using proprietary technologies from both companies: BioNTech’s proprietary immunomodulatory antibodies and Genmab’s DuoBody® technology platform. [BioNTech AG] Press Release Advaxis and Sorrento Form Collaboration to Evaluate Combinations of Advaxis’s Lm-LLO Immunotherapy Technology and Sorrento’s Immunomodulatory Antibodies Advaxis, Inc. has entered into a non-exclusive research and clinical trial collaboration agreement with Sorrento Therapeutics, Inc. to evaluate combinations of Advaxis’s Lm-LLO cancer immunotherapy technology platform, including ADXS-HPV, ADXS-PSA and ADXS-HER2, with Sorrento’s fully human antibodies targeting immune checkpoints, including GITR, OX40, LAG-3 and TIM-3. [Advaxis, Inc.] Press Release Sorrento Establishes TNK Therapeutics Subsidiary with Focus on Cellular Immunotherapies Sorrento Therapeutics, Inc. announced that it has formed a wholly-owned subsidiary, TNK Therapeutics, Inc. This subsidiary will focus on developing CAR.TNKs (chimeric antigen receptor tumor-attacking neukoplasts®) as well as other complementary cellular and immunotherapies targeting both solid tumors and hematological malignancies. [Sorrento Therapeutics, Inc.] Press Release Texas A&M Researchers Looking to Microbiota to Advance Personalized Medicine The host-microbiota connection serves as the driving force for a multi-institutional team of researchers led by Robert Alaniz, Ph.D., assistant professor at the Texas A&M College of Medicine. Their work, which recently received a $2 million grant from the National Institutes of Health, focuses on understanding how the microbiota regulate T-cells. [Texas A&M College of Medicine] Press Release Cancer Prevention and Research Institute of Texas Awards 41 New Grants The Cancer Prevention and Research Institute of Texas awarded 28 grants through its academic research program, 11 grants through its prevention program and two grants through its product development research program. [Cancer Prevention and Research Institute of Texas] Press Release Researcher Awarded $4.9 Million Grant from California Institute for Regenerative Medicine Shaomei Wang, MD, PhD, a research scientist in the Eye Program at the Cedars-Sinai Board of Governors Regenerative Medicine Institute, received a $4.9 million grant from the California Institute for Regenerative Medicine to advance her work in retinitis pigmentosa, a type of degenerative retinal disease. [Cedars-Sinai] Press Release Genocea Announces Positive Top-Line Phase II Data for Genital Herpes Immunotherapy GEN-003 Genocea Biosciences, Inc. announced positive top-line data from a Phase II dose optimization trial evaluating GEN-003 for the treatment of genital herpes. [Genocea Biosciences, Inc.] Press Release Alnylam Receives Orphan Drug Designation from the United States Food & Drug Administration for Revusiran, an Investigational RNAi Therapeutic for the Treatment of Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis) Alnylam Pharmaceuticals, Inc. announced that the United States Food & Drug Administration has granted Orphan Drug Designation to revusiran, an investigational RNAi therapeutic, for the treatment of ATTR amyloidosis. [Alnylam Pharmaceuticals, Inc.] Press Release |