Personalized Medicine through Genomic Analysis and Molecular Diagnostics
March 31, 2008 | Boston, Massachusetts
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Germinal Cells Can Become Embryonic Stem Cells
Primordial germinal cells, which are precursors to spermatozoids, apparently have the capacity of turning into embryonic stem cells.
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Mechanism by which Signaling Pathways Regulate Growth and Differentiation of Adult Muscle Stem Cells is Revealed
A group of scientists at the Burnham Institute for Medical Research in La Jolla, CA, analyzed the mechanism by which certain cellular signaling cues cause epigenetic modifications when released within the regenerative microenvironment, thus controlling the expression of genes that regulate growth and differentiation of muscle stem cells that repair injured muscle.
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Stem Cells Show Power to Predict Disease, Drug Toxicity
For the first time, scientists have used human embryonic stem cells to predict the toxic effects of drugs and provide chemical clues to diagnosing disease.
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PET and Bioluminescent Imaging Aid Evaluation of Stem Cells’ Potential for New Ways to Treat Disease
Using positron emission tomography imaging with bioluminescence—the light produced by a chemical reaction within an organism—researchers are starting to understand the behavior of transplanted or implanted stem cells that may one day be used to develop new treatments for disease.
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Australian Stem Cell Scientist on Target to Prevent Age-related Loss of Brain Function
Stem cell scientists are developing a novel approach to slow or possibly prevent the cognitive decline that typically occurs with advancing age.
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Human Embryonic Stem Cell Derived Bone Tissue Closes Massive Skull Injury
There are mice in Baltimore whose skulls were made whole again by bone tissue grown from human embryonic stem cells.
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Replacing The Cells Lost In Parkinson Disease
Researchers at the Karolinska Institue, Sweden, have identified a new source for dopamine (DA) cells that provided marked benefit when transplanted into mice with a parkinson disease (PD)-like disease.
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Bone Marrow Cell Transplants Help Nerve Regeneration
A study carried out by researchers at the Kyoto University School of Medicine has shown that when transplanted bone marrow cells containing adult stem cells are protected by a 15mm silicon tube and nourished with bio-engineered materials, they successfully help regenerate damaged nerves. The research may provide an important step in developing artificial nerves.
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Cell Transplants Hold Promise for Heart Attack Survivors
Working with mice, scientists strengthened the heart’s electrical system to prevent it from going haywire.
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ViRexx Announces Pivotal OvaRex(R) MAb Trial Results Fail to Achieve Statistical Significance
ViRexx Medical Corp. has announced that preliminary analysis of results from the two Phase III clinical trials of OvaRex(R) MAb for the treatment of advanced ovarian cancer showed that the studies failed to reach statistical significance.
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Patients Who Undergo a ‘Mini Transplant’ Have Similar Outcomes Regardless of Whether Stem Cell Donor is Related or Unrelated
People who undergo nonmyeloablative stem-cell transplants, or “mini transplants,” for leukemia, lymphoma and other blood cancers have comparable outcomes regardless of whether they receive tissue-matched stem cells from a related or unrelated donor, according to new findings by researchers at Fred Hutchinson Cancer Research Center.
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ABSTRACTS, REVIEWS AND SPECIAL REPORTS
Generation of Induced Pluripotent Stem Cells Without Myc From Mouse and Human Fibroblasts
The researchers describe a modified protocol for the generation of iPS cells that does not require the Myc retrovirus.
Abstract
Adipose-derived Stem Cells and Chondrogenesis
This review discusses the application of Adipose-derived stem cell to cartilage formation.
Abstract
JOB OPPORTUNITIES
Biomedical Equipment Technician
Los Angeles, CA (Cedars-Sinai Medical Center)
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Quality Manager
Singapore (Singapore Cord Blood Bank)
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Clinical Development Research Associate
Poway, California (VetStem)
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Islet Cell Associate Research Director
Irvine, CA (University of California, Irvine)
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