 | | Vol. 12.43 – 12 November, 2020 |
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| Using human cord tissue‐derived MSCs (hCT‐MSCs), scientists demonstrated that hCT‐MSCs directly interact and reprogram monocytes and macrophages.
[Stem Cells] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Considering the most important signaling pathways involved in the self-renewal of hematopoietic stem cells, CB-CD34+ cells were expanded with cytokines in the presence of seven small molecules including SB, PD, Chir, Bpv, Pur, Pμ, and NAM.
[Stem Cell Research & Therapy] |
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| A model of allergic rhinitis in BALB/c mice was established and evaluated to provide experimental subjects for further research. Preparation of human umbilical cord MSCs, including isolation, expansion culture, passaging, cryopreservation, and preparation of cell suspensions, provided materials for experimental research and clinical treatment.
[Scientific Reports] |
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| Researchers report the ability of photobiomodulation therapy to significantly enhance the engraftment efficacy of human umbilical cord hematopoietic stem cells and progenitor cells.
[Scientific Reports] |
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| A prospective single-center study that included analysis of umbilical cord blood of term and preterm neonates who were born from March 2017 to November 2017. Using ELISA analysis, 13 cytokines were simultaneously quantified and correlated with the development of early-onset sepsis.
[Pediatric Research] |
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| Scientists assessed the clinical and functional impact of autologous umbilical cord blood-derived mononuclear cells therapy when given to patients with Hypoplastic Left Heart Syndrome at Stage II surgery.
[Seminars in Thoracic and Cardiovascular Surgery] |
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| The umbilical cords were investigated by the histomorphological method and the number of Wharton’s jelly (WJ)-MSC were detected by flow-cytometry using the CD90, CD44, CD105, and CD73 markers in WJ isolated from fresh umbilical cords.
[Molecular Biology Reports] |
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| Xeno-free media showed potential for safe use for human clinical treatment. However, the influences of these xeno-free media on MSCs are various and any xeno-free medium should be examined prior to being used for MSC cultures.
[Tissue Engineering and Regenerative Medicine] |
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| Cynata Therapeutics Limited announced that the Phase III SCUlpTOR Trial of CYP-004, Cynata’s Cymerus™ MSC product for osteoarthritis, has now commenced.
[Cynata Therapeutics Limited (GlobeNewswire, Inc.)] |
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| Mesoblast Limited announced that the randomized controlled Phase III trial of remestemcel-L in patients with moderate to severe acute respiratory distress syndrome (ARDS) due to COVID-19 infection had received a recommendation to continue from the independent Data Safety Monitoring Board following completion of the trial’s second interim analysis.
[Mesoblast Limited] |
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| July 22 – July 23, 2021
Berlin, Germany |
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| | New York Blood Center – New York, New York, United States |
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| | Stanford University – Stanford, California, United States |
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| | United States Drug Testing Laboratories, Inc. – Des Plaines, Illinois, United States |
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| | Sanford Research – Sioux Falls, South Dakota, United States |
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| | The University of Chicago – Chicago, Illinois, United States |
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