Cord Blood News 11.17 May 9, 2019 | |
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TOP STORYSingle-Cell Transcriptomic Landscape of Nucleated Cells in Umbilical Cord Blood Scientists report the transcriptomes of 17,637 umbilical cord blood cells, covering 12 major cell types, many of which can be further divided into distinct subpopulations. [Gigascience] Full Article | |
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PUBLICATIONS(Ranked by impact factor of the journal)Single Cell Transcriptomic Analysis of Human Mesenchymal Stem Cells Reveals Limited Heterogeneity Researchers profiled the transcriptomes of 361 single MSCs derived from two umbilical cords (UC-MSCs). These UC-MSCs were harvested at different passages and stimulated with or without inflammatory cytokines. [Cell Death Dis] Full Article To investigate optimal unit selection for umbilical cord blood transplantation (UCBT), scientists conducted a registry-based study of 1355 adults with acute myeloid leukemia in first or second complete remission who underwent single-unit UCBT. [Bone Marrow Transplant] Abstract The authors explored possible mechanisms of action using next generation RNA sequencing to analyze the brain transcriptome profiles in rats with ischemic brain injury following umbilical cord blood stem cell therapy. [Cell Transplant] Full Article Investigators verified angiotensin II and transforming growth factor-beta 1 (TGF-β1) as potential cardiomyogenic differentiation inducers of amniotic fluid-derived-MSCs. [Int J Stem Cells] Abstract DNA extracted from buffy coat of cord blood samples were typed for HLA‐ A, B, C, DRB1 and DQB1 alleles by Illumina miniseq and the sequences were aligned, phased and mapped by Mia Fora software algorithms. [HLA] Abstract Subscribe to one of our other 19 science newsletters such as Hematopoiesis News & Cell Therapy News. | |
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REVIEWSBiological Functions of Mesenchymal Stem Cells and Clinical Implications The authors outline the fundamental and advanced concepts of MSC biological features and underline the biological functions of MSCs in their basic and translational aspects in therapy for degenerative and/or inflammatory diseases. [Cell Mol Life Sci] Abstract Visit our reviews page to see a complete list of reviews in the cord blood research field. | |
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INDUSTRY NEWSExCellThera Enters into a Manufacturing and Collaboration Agreement with New York Blood Center ExCellThera Inc. announced that it has entered into a manufacturing and collaboration agreement with Comprehensive Cell Solutions for the clinical grade production of ExCellThera’s lead cell therapy product, ECT-001. [ExCellThera Inc.] Press Release Tmunity Therapeutics, Inc. announced it has entered into an exclusive licensing and research collaboration with the University of California (UC) San Francisco aimed at advancing novel engineered T cell receptor therapies for rare and currently incurable pediatric conditions with high mortality rates. [Tmunity Therapeutics, Inc.] Press Release | |
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POLICY NEWSWhite House to Convene Committee to Address Research Obstacles The leaders of the White House Office of Science and Technology, National Institutes of Health, National Science Foundation, National Institute of Standards and Technology, and the Department of Energy’s science division have formed a committee “to address issues facing the U.S. research community,” President Donald Trump’s administration announced. [The Scientist] Editorial Black Academics Publish One-Fifth of South Africa’s Research The proportion of scientific articles published by academics in South Africa who are black, colored or of Indian origin has risen almost tenfold since the end of apartheid, to about one-third, finds a report on scholarly publishing in the country. [Nature News] Editorial
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EVENTSNEW International Society for Stem Cell Research (ISSCR) 2019 Annual Meeting Visit our events page to see a complete list of events in the community.
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JOB OPPORTUNITIESNEW Postdoctoral Researcher – Normal and Malignant Hematopoiesis (Karolinska Institutet) Postdoctoral Position – Stem Cell Transplant Immunology (University of Illinois at Chicago) Research Technician – Leukemia (VIB) Postdoctoral Researcher – Stem Cells and Erythropoiesis in MDS (Karolinska Institutet) Assistant, Associate, or Full-Professor Positions – Cancer Research (Brown University) Postdoctoral Research Fellow – Functional Genomics (Justus Liebig University Giessen) Postdoctoral Fellows – Hematological Malignancies and Cancer Immunology (Fox Chase Cancer Center) Postdoctoral Position – Mechanobiology (The University of Texas Health Science Center at Houston) Postdoctoral Position – Hematopoietic Stem Cells (Washington University School of Medicine) Faculty Positions – Cancer Research (Shenzhen University) Recruit Top Talent: Reach potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost.
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