Cord Blood News 11.22 June 13, 2019 | |
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TOP STORYTransplantation of allogeneic umbilical cord-derived MSCs significantly up-regulated peripheral blood CD1c+ dendritic cells and serum FLT3L. [Nat Commun] Full Article | |
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PUBLICATIONS(Ranked by impact factor of the journal)Scientists examined the effects of an intravenously transplanted combination of hUCB‐derived plasma into the 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine‐induced rat model of Parkinson’s disease. [J Cell Mol Med] Full Article The authors investigated the safety and efficacy of umbilical derived‐MSCs administered to children diagnosed with autism spectrum disorder. Efficacy was evaluated with the Autism Treatment Evaluation Checklist and the Childhood Autism Rating Scale, and with measurements of macrophage‐derived chemokine and thymus and activation‐regulated chemokine serum levels. [Stem Cells Transl Med] Full Article Nanofiber-Expanded Human CD34+ Cells Heal Cutaneous Wounds in Streptozotocin-Induced Diabetic Mice Researchers offer an aminated polyethersulfone nanofiber-expanded human umbilical cord blood-derived CD34+ cells effective therapy, tested in cutaneous wounds developed in streptozotocin-induced diabetic NOD/SCID mice. [Sci Rep] Full Article Investigators report isolation of viable human amniotic fluid-derived stem cells, labeled with multimodal iron oxide nanoparticles, and the effect on focal cerebral ischemia-reperfusion injury in Wistar rats. [Cell Transplant] Full Article The authors found that the administration of human umbilical cord-MSCs pretreated with angiotensin-II significantly inhibited pancreatic injury, as reflected by reductions of pancreatitis severity scores, serum amylase and serum lipase levels. [Biomed Pharmacother] Full Article Researchers compared the transfusion requirements of patients undergoing umbilical cord blood transplantation and haploidentical hematopoietic stem cell transplantation (HSCT) in a single institution with the aim of providing additional information for clinicians to choose the most adequate alternative graft for HSCT. [Eur J Haematol] Abstract Subscribe to one of our other 19 science newsletters such as Hematopoiesis News & Cell Therapy News. | |
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REVIEWSEnhancing the Therapeutic Potential of Mesenchymal Stem Cells with the CRISPR-Cas System The authors outline the evolution of MSC research and its applicability, and the progress of the CRISPR-Cas system from its discovery to the most recent clinical trials. [Stem Cell Rev Rep] Abstract Visit our reviews page to see a complete list of reviews in the cord blood research field. | |
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INDUSTRY NEWSMesoblast Limited announced it has expanded its partnership with JCR Pharmaceuticals Co. Ltd. in Japan to the use of MSCs for the treatment of newborns who lack sufficient blood supply and oxygen to the brain, a condition termed neonatal hypoxic ischemic encephalopathy. [Mesoblast Limited (GlobeNewswire, Inc.)] Press Release UCLA Professor’s Last Gift Will Support Research in Cancer and Stem Cell Biology Shortly before financier and UCLA professor Roy Doumani passed away in March, he and his wife, Carol, contributed $5.25 million to advance research in cancer and stem cell biology at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA. [University of California, Los Angeles] Press Release | |
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POLICY NEWSUS-China Tensions Leave Some Researchers on Edge Changing policy has left academics uncertain about what is legal for foreign involvement in research, and increased hostility and bureaucracy have led students and scholars to seek opportunities elsewhere. [The Scientist] Editorial Emory Scientist Was Told to Vacate His Office. He Says Move Is Reprisal for Activism on Asian Ties A tenured professor of anesthesiology at Emory University in Atlanta says he is being targeted by school administrators because of a letter he and other faculty members sent its president urging her to defend foreign scientists on campus and the value of international collaborations. [ScienceInsider] Editorial
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EVENTSNEW 5th Annual Cell & Gene Therapy Congress Visit our events page to see a complete list of events in the community.
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JOB OPPORTUNITIESNEW Postdoctoral Studies – Normal and Aberrant Hematopoiesis (Karolinska Institutet) NEW Postdoctoral Position – Leukemia (University of California, San Francisco) Assistant Director – Cell Therapy Laboratory (MD Anderson Cancer Center) Research Associate – Oncology and Hematology (University of Manitoba) Researcher – Hematological and Cardiovascular Molecular Epidemiology (Uppsala University) Research Fellow – Hematology, Blood Disorders and Stem Cell Biology (New York Blood Center) Postdoctoral Position – Epigenetic Regulation of Hematopoietic Stem Cells (Karolinska Institutet) Postdoctoral Scientist – Hematopoietic Stem Cell Research (DKFZ / HI-STEM) Postdoctoral Position – Stem Cell Transplant Immunology (University of Illinois at Chicago) Recruit Top Talent: Reach potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost.
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