 | | Vol. 11.28 – 3 December, 2020 |
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| Expression of miR-451a and a disintegrin and metalloprotease 10 in HCC tissues and adjacent normal tissues was determined. The exosomes were extracted from hucMSCs and co-cultured with Hep3B and SMMC-7721 cell lines.
[RNA Biology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| A stable animal model was established via an intratracheal injection of 5 mg bleomycin (BLM). One single transplantation of 2.5 × 107 human umbilical cord MSCs or initiation of daily oral nintedanib/pirfenidone administration was performed on day 21 following BLM damage.
[Stem Cell Research & Therapy] |
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| Researchers conducted a small sample, single arm, pilot trial. In addition to standard therapy, they performed four rounds of transplantation of umbilical cell‐MSCs in sixteen patients with severe and critically severe COVID‐19.
[Cell Proliferation] |
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| Scientists employed a technique of highly sensitive HLA-specific quantitative-PCR assays targeting polymorphisms unique to the cord blood (CB) mother to assay CB-maternal microchimerism (MMc) in patients post-CB transplantation. After additional exclusion criteria, CB-MMc was evaluated at multiple timepoints in 36 patients.
[Bone Marrow Transplantation] |
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| Researchers assessed effects of the transition from liquid nitrogen to dry ice on cell viability; apoptosis; phenotype; proliferation; immunomodulation; and clonogenesis; and validated dry ice-based transport of umbilical cord-MSCs to clinics.
[Journal of Translational Medicine] |
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| After extraction and identification of human umbilical cord MSCs (HMCs)-derived extracellular vesicles, ischemia reperfusion rat models were established and treated with HMC-EVs to measure pathological damage, apoptosis and inflammation in brain tissues.
[Neurochemical Research] |
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| Investigators examined the effects of human amniotic membrane MSCs‐conditioned medium on ovalbumin (OVA)‐induced asthma. 48 hours after the last challenge, serum and bronchoalveolar lavage fluid samples were collected and used for evaluation of inflammatory factors and cells, respectively.
[Experimental Physiology] |
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| MSCs obtained from various sources have diverse capabilities of secreting many different cytokines, growth factors, and chemokines. It is believed that the salutary effects of MSCs from different sources are not alike in terms of repairing or reformation of injured skeletal tissues.
[Stem Cell Research & Therapy] |
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| To mark the end of Diabetes Awareness Month, Sonia Sidhu, Member of Parliament for Brampton South, on behalf of the Honourable Patty Hajdu, Minister of Health, announced an investment of $6 million through the CIHR-JDRF Partnership to Defeat Diabetes for two Canadian research teams to accelerate the development of stem cell-based therapies for the treatment of type 1 diabetes.
[Juvenile Diabetes Research Foundation] |
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| Three academic scientists at two North Carolina universities are among the recipients of the first seed grants from the Amnion Foundation for research projects that will study cells derived from birth tissue to better understand fetal health and cancer.
[Amnion Foundation (WRAL TechWire)] |
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| October 27 – October 29, 2021
Tokyo, Japan |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | University of Illinois at Chicago College of Medicine – Chicago, Illinois, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | New York Blood Center – New York, New York, United States |
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| | Stanford University – Stanford, California, United States |
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