 | | Vol. 11.29 – 10 December, 2020 |
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| Wharton’s jelly (WJ)-MSCs were cocultured with or without endometrial stromal cells (ESCs) damaged by mifepristone. TUNEL staining assays, EdU proliferation assays, flow cytometry apoptosis assays, and western blot assays were performed to observe the reparative effect of WJ-MSCs on damaged ESCs.
[Stem Cell Research & Therapy] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Extracellular vesicles derived from unprimed human umbilical cord mesenchymal stem cells or human umbilical cord stem cells (HCPT)-extracellular vesicles (EVs) were isolated and characterized. A rat model of Achilles tendon injury was used to confirm the anti-adhesion effect of HCPT-EVs and compared with that of unprimed EVs in vivo.
[Stem Cell Research & Therapy] |
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| Researchers report here that ACE2 was highly expressed in adult bone marrow, adipose tissue or umbilical cord‐derived MSC. On the other hand, placenta‐derived MSC expressed low levels of ACE2 but only in early passages of cultures.
[Stem Cells Translational Medicine] |
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| Scientists investigated the restorative effect of placenta derived (PD)-MSCs on injured ovaries in ovariectomized rats and the ability of intravenous transplantation of PD-MSCs to enhance ovarian vasculature and follicular development.
[Laboratory Investigation] |
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| Investigators demonstrated a method to generate shortcut neural progenitor cells (sNPCs) from blood mononuclear cells and present a detailed comparison of these sNPCs with NPCs obtained from the same blood samples through stable induced pluripoent stem cells clones and a subsequent neural differentiation
[International Journal of Molecular Sciences] |
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| Slit2 interacted with Robo4 that was highly expressed in RAW 264.7 macrophages: their interaction increased the adhesive ability of RAW 264.7 cells and inhibited migration.
[Molecular Human Reproduction] |
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| Umbilical-cord blood vessels were isolated for decellularization and to establish endothelial cell culture. Cultured cells were characterized by immunophenotype, gene expression and in vitro angiogenesis assay.
[Journal of Materials Science-Materials in Medicine] |
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| To minimize the effect of fluctuation in ambient temperature on stored cells, scientists designed an automatic cryopreservation system that handles cells under controlled temperatures.
[Cryobiology] |
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| The authors describe two aspects of the clinical therapeutic effects of human umbilical cord (hUCs)-MSCs. They explain the benefits and mechanisms of HUC-MSC treatment in various diseases.
[Stem Cell Research & Therapy] |
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| Pluristem Therapeutics, Inc. announced that the independent Data Monitoring Committee (DMC) of its global pivotal Phase III study for the treatment of critical limb ischemia (CLI) issued its recommendation letter following the interim analysis.
[Pluristem Therapeutics, Inc.] |
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| April 5 – 16, 2021
Virtual |
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| | National University of Ireland Galway – Galway, Ireland |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | University of Illinois at Chicago College of Medicine – Chicago, Illinois, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | New York Blood Center – New York, New York, United States |
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