Cord Blood News 11.46 November 28, 2019 | |
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TOP STORYInvestigators tested the effects, dose-response, and mechanisms of action of cryopreserved, xenogeneic-free human umbilical cord MSCs in a rat model of fecal peritonitis, and examined the role of heme oxygenase-1 in protection. [Anesthesiology] Abstract | |
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PUBLICATIONS(Ranked by impact factor of the journal)Researchers examined the feasibility and effectiveness of human cord tissue‐derived MSC administration given via the intranasal route. Human umbilical cord tissue MSCs were isolated, characterized, and given intranasally to a hyperoxia‐induced rat model of bronchopulmonary dysplasia. [Stem Cells Transl Med] Full Article Scientists provide an experimental model for elucidating the therapeutic effects of umbilical cord MSCs (UCMSCs) in inflammatory bowel disease (IBD). Thwy provide a theoretical basis and method for the clinical treatment of IBD using UCMSCs. [Sci Rep] Full Article The authors compared the chondrogenic potential of equine MSCs derived from bone marrow and umbilical cord blood, at their undifferentiated status to check if one cell source is better proned, and after chondrogenic-induced differentiation. [Stem Cell Rev Rep] Abstract Investigators used a validated spinal cord injury experimental model in which an intraparenchymal injection of kainic acid into the C5 segment of rat spinal cord induced an excitotoxic lesion. Three days later, experimental animals were treated with an intracerebroventricular injection of human umbilical cord MSCs whereas control group only received saline solution. [Stem Cell Rev Rep] Abstract Scientists elucidated whether miR-29a and/or together with transplantation of mesenchymal stem cells isolated from umbilical cord Wharton’s jelly could aid in skeletal muscle healing and putative molecular mechanisms. [Int J Mol Sci] Full Article Subscribe to one of our other 19 science newsletters such as Hematopoiesis News & Cell Therapy News. | |
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REVIEWSThe authors conducted a systematic review to inquire into the safety, tolerability, and efficacy of MSC therapies in multiple sclerosis. [Mult Scler Relat Disord] Abstract Visit our reviews page to see a complete list of reviews in the cord blood research field. | |
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INDUSTRY NEWSAn innovative new major private-public partnership led by Harvard and MIT aims to accelerate one of the hottest and most promising areas of medical research: cell and gene therapy. [The Harvard Gazette] Press Release Hope Biosciences Receives FDA Approval to Commence Groundbreaking Clinical Trial for Alzheimer’s Hope Biosciences announced that FDA has approved a Phase I/II clinical trial evaluating safety and efficacy of Hope Biosciences’ autologous, adipose-derived MSCs for Alzheimer’s disease, in partnership with Altoida, Inc. [Hope Biosciences] Press Release | |
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POLICY NEWSPhD Students in China Report Misery and Hope In a Nature survey, only 55% of the Chinese students who responded to the survey said that they were at least partially satisfied with their PhD experience. For the 5,630 respondents outside China, the satisfaction rate was 72% [Nature News] Editorial Chinese Ministry Investigates Duplications in Papers by University President The Chinese education ministry is investigating scientific articles authored by high-profile immunologist and university president Cao Xuetao, following suggestions that dozens of papers contain potentially problematic images. Four journals also say they are examining papers from Cao. [Nature News] Editorial Stark Party Differences in ‘Brexit Election’ Could Shape Future of UK Science When representatives of each party took to a stage last week at the Royal Society in London, they all promised increased funding and easier immigration for scientists. But Brexit loomed over the discussion, says Sarah Main, director of the Campaign for Science and Engineering, an advocacy group in London. [ScienceInsider] Editorial
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EVENTSNEW FGF Signaling: Understanding Function and Devising Therapeutic Tools Visit our events page to see a complete list of events in the community.
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JOB OPPORTUNITIESNEW Head of Laboratory – Cell Therapies (NHS Blood and Transplant) Scientist – Hematopoietic Stem and Progenitor Cell Biology (STEMCELL Technologies Inc.) Research Fellow – Iron-Altered Hematopoiesis (New York Blood Center) Doctoral Student Position – Immunology and Gene Therapy (Karolinska Institutet) Postdoctoral Fellow – Erythropoiesis (Mount Sinai School of Medicine) PhD Studentships – Molecular and Cell Biology (University of Oxford) Faculty Position – Stem Cell Biology and Regenerative Medicine (Yale University School of Medicine) Research Assistant – Stem Cells and Engineering (New York Blood Center) Group Leader – Vascular Biology, Hematopoiesis or Cardiovascular Disease (University of Wurzburg) Postdoctoral Fellow – Normal and Malignant Hematopoiesis (Versiti Blood Research Institute) PhD Positions – Cancer and Developmental Biology (Peter MacCallum Cancer Centre) Recruit Top Talent: Reach potential candidates by posting your organization’s career opportunities on the Connexon Creative Job Board at no cost.
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