 | | Vol. 12.27 – 23 July, 2020 |
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| Researchers investigated the efficacy of a biomimetic hydroxyapatite-gradient scaffold isolated from adipose tissue with umbilical cord derived MSCs on the regeneration of the structure of the tendon-to-bone interface by analyzing the histological and biomechanical changes in a rat repair model.
[Acta Biomaterialia] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Amniotic fluid stem cells were isolated as CD117-positive cells from human amniotic fluid. Three-day-old rat pups were intraperitoneally treated with lipopolysaccharide to mimic neonatal sepsis.
[Stem Cell Research & Therapy] |
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| A cohort of eight pediatric cereberal palsy (CP) patients with intact corticospinal tracts from a randomized, placebo‐controlled trial of autologous umbilical cord blood stem‐cell therapy in CP children was included in this study.
[Journal of Magnetic Resonance Imaging] |
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| Investigators demonstrated for the first time that angiotensin-converting enzyme 2 (ACE2) and the entry-facilitating transmembrane protease TMPRSS2 were expressed on very small CD133+CD34+Lin−CD45− cells in human umbilical cord blood, which could be specified into functional hematopoietic stem cells and endothelial progenitor cells.
[Stem Cell Reviews and Reports] |
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| Human umbilical cord (hUC)-MSCs were administered into chronic unpredictable mild stress model mice through the tail vein once a week for four weeks. After the administration of hUC-MSCs, the depression-like and anxiety-like phenotypes, neuronal histopathology, synaptic-related protein expression and inflammatory index of the mice were assessed.
[Brain Research Bulletin] |
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| Scientists investigated the effects of preeclampsia in pregnancy on the stemness and differentiation potency of umbilical cord blood-hematopoietic stem cells.
[BMC Pregnancy and Childbirth] |
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| Researchers highlight how mitochondrial metabolism determines hematopoietic stem cell (HSC) fate, and especially focus on the links between mitochondria, endoplasmic reticulum, and lysosomes in HSC metabolism.
[Developmental Cell] |
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| For the hundreds of thousands of people enrolling in clinical trials every year—and for whom experimental therapies can offer a last hope—a new report provides some welcome news: Enrollment in clinical studies in the United States is on the rebound after disruptions caused by the COVID-19 pandemic.
[ScienceInsider] |
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| A historic €1.8-trillion (US$2.1-trillion) budget deal reached by European Union (EU) leaders to fund its next seven years — and its recovery from the coronavirus pandemic — has left scientists and research advocates disappointed.
[Nature News] |
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| August 19 – August 21
Virtual |
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| | The University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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| | University of Maryland – Baltimore, Maryland, United States |
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| | Northwestern University – Chicago, Illinois, United States |
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| | Columbia University – New York, New York, United States |
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| | Duke University – Durham, North Carolina, United States |
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