| Vol. 12.40 – 15 October, 2020 |
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| HIV-unexposed and HIV-exposed uninfected infant cord blood monocytes were treated with Bacillus Calmette-Guerín (BCG) and transcriptionally profiled with the Nanostring nCounter platform. Differential expression and pathway enrichment analyses were performed, and transcripts were identified with enhanced or dampened BCG responses. [AIDS] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| WJ-MSCs were encapsulated in 3D hydrogels derived from human fibrin or platelet lysate and the oxygen level was adjusted to physiological normoxia (5% O2). [Scientific Reports] |
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| Scientists investigated the effectiveness of hyaluronan–methylcellulose hydrogels loaded with WJ-MSCs in vitro and in a rat coccygeal intervertebral disc degeneration model. [International Journal of Molecular Sciences] |
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| Investigators evaluated the osteogenic capability of placental stem cell-derived extracellular vesicles (EVs) and compared them to the well-characterized bone marrow MSC-derived EVs. EVs were extracted from three designated time points after osteogenic differentiation. [Tissue Engineering] |
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| Researchers found that human umbilical cord MSCs-derived small extracellular vesicles were successfully absorbed by lung tissue after intratracheal administration, and remained in the lungs for at least 72 hours. [Stem Cells and Development] |
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| The structure of the rabbit umbilical cord was analyzed and compared with that of human umbilical macroscopically and histologically. Scientists isolated, cultured, and identified the proliferative activity and immunological characteristics of rabbit umbilical cord MSCs in vitro using mixed lymphocyte reaction, flow cytometry, and ELISA test. [The Journal of Gene Medicine] |
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| The authors give a brief description of MSCs, their sources and markers, and the different attempts that have been made towards achieving the goal of differentiating MSCs into neurons. [Journal of Molecular Neuroscience] |
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| Scientists review the current evidences and explore the potential therapeutic use of allogenic umbilical cord (UC) and/or Wharton’s jelly (WJ)-derived MSCs for the treatment of COVID-19. [Human Cell] |
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| Sorrento Therapeutics, Inc. announced that it has entered into an exclusive license agreement with Personalized Stem Cells, Inc. to acquire global rights to its adipose-derived MSCs for patients suffering from acute respiratory distress syndrome associated with COVID-19, which have been cleared for a Phase I clinical trial by the FDA. [Sorrento Therapeutics, Inc.] |
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| April 11 – April 13, 2021 San Diego, California, United States |
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| Sanford Research – Sioux Falls, South Dakota, United States |
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| The University of Chicago – Chicago, Illinois, United States |
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| University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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| Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| University of Miami – Miami, Florida, United States |
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