 | | Vol. 12.41 – 22 October, 2020 |
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| Investigators found that human T cell leukemia virus type 1 proviral DNA was present in the placental villous tissues of the fetuses of nearly half of pregnant carriers and in a small number of cord blood samples.
[Journal of Clinical Investigation] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists performed whole-genome bisulfite sequencing of 152 umbilical cord blood samples from the MARBLES and EARLI high-familial risk prospective cohorts to identify an epigenomic signature of autism spectrum disorder at birth.
[Genome Medicine] |
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| Researchers tested the hypothesis that systemic amnion–derived multipotent progenitor (AMP) cell administration could suppress both optic neuritis and myelitis in amnion epithelial cells (EAE). Intravenous and intraperitoneal administration of AMP cells significantly reduced ascending paralysis and attenuated visual dysfunction in EAE mice.
[Neurotherapeutics] |
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| Umbilical cord-MSC culture was conducted under xeno- and serum-free conditions. Four patients with established bronchopulmonary dysplasia were enrolled in this study between May 25, 2018, and December 31, 2018.
[Journal of Translational Medicine] |
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| Scientists compared the effects of three tissue‐derived MSCs in vivo on colon tumor xenograft growth. Then, they analyzed the tropism of bone marrow‐derived MSCs toward normal intestinal epithelial cells, parental colon cancer cells, CD133−/CD44−, and CD133+/CD44+ colon cancer cells in vitro.
[Journal of Cellular Physiology] |
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| Using cord blood mononuclear cells and cord plasma isolated from infants born to women with a high BMI compared to women with a normal BMI, the authors evaluated differences in immune cell populations using single‐cell mass cytometry.
[American Journal of Reproductive Immunology] |
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| Patients underwent treatment of full-thickness chondral injury in the osteoarthritic knee with high tibial osteotomy and implantation of human umbilical cord-MSCs and were followed prospectively for a minimum of one year.
[International Orthopaedics] |
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| Platelet lysate (PL) had been shown to induce chondrogenic differentiation of human umbilical cord‐derived MSCs Scientists investigated whether long non‐coding RNA H19 was involved in this process. Human umbilical cord MSCs were isolated, identified, and cultured in 5% PL‐supplemented chondrogenic differentiation medium.
[Febs Open Bio] |
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| Investigators focus on summarizing the biological characteristics of human amniotic epithelial cells, therapeutic applications, and recent advances in treating various tissue injuries and disorders.
[Stem Cell Research & Therapy] |
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| Global Stem Cells Group (GSCG) signed a historic agreement with a company known as Bioscience Cell Factor- this Dubai-based healthcare company will allow GSCG to act as their representatives operating in both the Middle East and Latin America.
[Global Stem Cells Group] |
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| Bone Therapeutics has announced positive 24-month follow-up results for the Phase IIa study with the allogeneic cell therapy product, ALLOB, in patients undergoing lumbar spinal fusion procedures. ALLOB is their off-the-shelf allogeneic cell therapy platform consisting of human allogeneic bone-forming cells derived from cultured bone marrow MSCs from healthy adult donors.
[Bone Therapeutics S.A.] |
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| Sep 7 – 11, 2022
Woods Hole, Massachusetts, United States |
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| | University of Navarra – Pamplona, Spain |
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| | Sanford Research – Sioux Falls, South Dakota, United States |
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| | The University of Chicago – Chicago, Illinois, United States |
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| | University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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