| Vol. 12.41 – 29 October, 2020 |
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| The authors established a standardized culture platform using xeno- and serum-free commercial media for expansion of MSCs derived from umbilical cord, bone marrow and adipose-derived and examined their functional characteristics. [Cytotherapy] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators extracted collagen from human amniotic membrane and umbilical cord, which are treated as medical waste and compared its physico-chemical properties. [International Journal of Biological Macromolecules] |
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| After C–C motif chemokine ligand 2 (CCL2)-overexpressing human umbilical cord (hUC)-derived MSCs were intravenously transplanted with mannitol in rats with middle cerebral arterial occlusion, scientists compared the differences between four different treatment groups: mannitol + CCL2-overexpressing hUC-MSCs, mannitol + naïve hUC-MSCs, mannitol only, and control. [International Journal of Molecular Sciences] |
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| Investigators examined the expression of ACE2, to which SARS-CoV-2 Spike protein binds to facilitate viral entry, in cord blood derived hematopoietic stem cells/hematopoietic progenitor cells and in peripheral blood derived immune cell subtypes. [Stem Cell Reviews and Reports] |
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| To establish the most robust and efficient way to measure the Treg content of previously cryopreserved cord blood units, researchers compared the enumeration of Treg and CD3+ cells using flow cytometry and an epigenetic, DNA-based methodology. [PLoS One] |
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| Researchers investigated the proliferation of umbilical cord blood–derived endothelial progenitor cells and the differentiation efficiency toward corneal endothelial cell-like cells induced by rho-associated protein kinase inhibitor Y-27632 and to determine the most effective strategy for repairing corneal endothelium injuries in rabbits. [Cornea] |
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| Stem cells can be induced to differentiate to corneal epithelial cells and used in treatment in corneal epithelium deficiency. Multipotent stem cells (MSCs) and pluripotent stem cells (ESCs and iPSCs) are promising cells to address the problem. Various protocols have been developed to induce differentiation of the stem cells into corneal epithelial cells. [International Journal of Molecular Sciences] |
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| Bayer AG announced the acquisition of Asklepios BioPharmaceutical, Inc., a US-headquartered biopharmaceutical company specialized in the research, development and manufacturing of gene therapies across different therapeutic areas. [Bayer AG] |
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| May 16 – May 21, 2021 Lucca, Italy |
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| National University of Ireland Galway – Galway, Ireland |
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| University of Navarra – Pamplona, Spain |
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| Sanford Research – Sioux Falls, South Dakota, United States |
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| The University of Chicago – Chicago, Illinois, United States |
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| University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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