 | | Vol. 12.00 – 7 January, 2021 |
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| Intravascular cell labeling, cell transplantation, and fate-mapping studies established that classical CD14+ blood monocytes derived from ematopoietic stem and progenitor cells migrated into lung tissue and gave rise to human interstitial and alveolar macrophages.
[Immunity] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators evaluated two properties of a novel source of MSCs-first trimester human umbilical cord perivascular cells-that may render them a promising candidate for chemotherapeutic gonadal injury prevention.
[Cancer Letters] |
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| Scientists determined the safety and explored efficacy of umbilical cord mesenchymal stem cell infusions in subjects with COVID‐19 scute respiratory distress syndrome. A double‐blind, Phase I/IIa, randomized, controlled trial was performed.
[Stem Cells Translational Medicine] |
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| The authors demonstrated that umbilical cord tissue-MSCs could be easily isolated without expensive enzymatic treatment or columns and reprogramed well using episomal vectors, which could allow for the removal of the reprogramming factors after a few passages.
[Cells] |
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| Researchers developed a combinatorial system using stable lentiviral delivery of single guide RNA followed by transient transfection of Cas9 mRNA by electroporation in human cord blood-derived CD34+ hematopoietic stem and progenitor cells.
[Scientific Reports] |
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| Investigators determined the full proteome and examine cell viability in nine commercial amnion products using an unbiased bottom-up shotgun proteomics approach and confocal microscopy.
[Cartilage] |
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| Hematopoietic stem progenitor cells from cord blood were cocultured with growth-arrested adipose mesenchymal stromal cells. Commitment-related transcriptional and secretory profiles as well as hematopoiesis-supportive activity of intact and osteo-induced MSCs were examined.
[Life Sciences] |
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| | Scientists showed that HUCMSCs+ultra short wave therapy improved motor function of spinal cord injury rats, together with decreased infiltration of CD3+ T cells, and decreased induction of microglia and A1 astrocytesbr />[Life Sciences] |
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| Amniotic fluid stem cells (AFSCs), a relatively novel source of stem cells, have been exploited for their ability of pluripotent differentiation. In addition, since AFSCs are weakly positive for the major histocompatibility class II molecules, they may have high immune tolerance.
[International Journal of Molecular Sciences] |
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| IMAC Holdings, Inc. has completed the first infusion of its investigational compound utilizing umbilical cord-derived allogenic MSCs in its Phase I clinical trial for the treatment of bradykinesia, or the gradual slowing and loss of spontaneous body movement, due to Parkinson’s disease.
[IMAC Holdings, Inc.] |
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| February 3 – 23, 2021
Virtual |
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| | STEMCELL Technologies, Inc. – Burnaby, British Columbia, Canada |
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| | Fondazione Human Technopole – Milan, Italy |
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| | Columbia University Medical Center – New York, New York, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| | St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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