 | | Vol. 12.03 – 28 January, 2021 |
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| A novel strategy of sandwich-type encapsulation of the conjugated polymer interlayer in the crystalline SiO2 core + shell was developed, which worked well to avoid the aggregation-induced fluorescence quenching problem by homogeneously dispersing PFTBT and suppressing intermolecular π–π stacking.
[ACS Applied Materials & interfaces] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists investigated the efficacy of human umbilical Wharton’s jelly-derived MSCs and their extracellular vesicles in a rat model of optic nerve crush.
[Stem Cell Research & Therapy] |
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| The authors found that injected human umbilcal cord-derived exosomes were able to access the site of ischemic damage and could be internalized by cells both in vivo and in vitro.
[Aging-Us] |
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| In order to understand the intrapopulation heterogeneity, various fractions of human amniotic fluid stem cells were isolated using the Celector® profile and live imaging feature. The gene expression profile of each fraction was analyzed using whole-transcriptome sequencing.
[Cells] |
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| Investigators assessed the immunosuppressive effects of human amnion-derived MSC in a xenogeneic graft-versus host disease NOD/Shi-scid IL2rγnull mouse model using human peripheral blood mononuclear cells.
[Scientific Reports] |
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| The immunomodulatory potency of human umbilical cord‐derived mesenchymal stem cells was demonstrated in the in vivo middle cerebral artery occlusion‐induced brain injury rat model and in vitro THP‐1‐derived macrophages model.
[Cell Biology International] |
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| Researchers characterized the protein secretome of adipose, bone marrow, placenta, and Wharton’s jelly-derived human MSCs by using conditioned media and analyzing the secretome by mass spectrometry and follow-up bioinformatics.
[International Journal of Molecular Sciences] |
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| MSCs demonstrate in vitro and in vivo pro-angiogenic, immuno-suppressive, and anti-fibrotic properties and appear as a promising stem cell therapy type, that may target the key pathological features of systemic sclerosis disease.
[Autoimmunity Reviews] |
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| The authors review current findings regarding sex differences observed in the umbilical cord, a widely used source of research samples, both in the blood and in the circulating cells, as well as in the different cellular models obtainable from it.
[Life] |
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| Sorrento Therapeutics, Inc. announced preliminary results from its Phase Ib study of human allogeneic adipose-derived mesenchymal stem cells for patients suffering from COVID-19-induced acute respiratory distress or acute respiratory distress syndrome.
[Sorrento Therapeutics, Inc.] |
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| March 14 – 17, 2021
Virtual |
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| | Blood Research Institute – Milwaukee, Wisconsin, United States |
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| | The Jackson Laboratory – Bar Harbor, Maine, United States |
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| | St. Jude Children’s Hospital – Memphis, Tennessee, United States |
| | | University of Colorado – Aurora, Colorado, United States |
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| | Columbia University Medical Center – New York, New York, United States |
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