CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Tregs Prevent GvHD and Promote Immune Reconstitution in HLA-Haploidentical Transplantation The present study evaluated the impact of early infusion of Tregs, followed by conventional T cells, on GvHD prevention and immunological reconstitution, in 28 patients with high risk hematological malignancies who underwent HLA-haploidentical hematopoietic stem cell transplantation. [Blood] Hoxb4-YFP Reporter Mouse Model: A Novel Tool for Tracking HSC Development and Studying the Role of Hoxb4 in Hematopoiesis Hoxb4 expression does not appear to correlate with the cycling status of fetal liver hematopoietic stem cells (HSCs), although highly proliferative HSCs from young bone marrow show strong Hoxb4 expression. [Blood] Efficient Human iPS Cell Derivation by a Non-Integrating Plasmid from Blood Cells with Unique Epigenetic and Gene Expression Signatures The analysis suggested that newborn cord blood and adult peripheral blood mononuclear cells (MNCs) display unique signatures that are closer to induced pluripotent stem cells (iPSCs) and human embryonic stem cells (ESCs) than age-matched fibroblasts to iPSCs/ESCs, thus making blood MNCs an attractive cell choice for the generation of integration-free iPSCs. [Cell Res] Chondrogenesis from Human Placenta-Derived Mesenchymal Stem Cells (hPMSCs) in 3D Scaffolds for Cartilage Tissue Engineering It was concluded that the alginate/nano-sized calcium deficient hydroxyapatite/arginine-glycine-aspartate mixed gel in the aforementioned system could provide a 3D environment for the chondrogenesis of human placenta-derived mesenchymal stem cells, while the poly(D,L-lactide-co-glycolide) precision scaffold could provide the dimensional stability of the whole construct. [Tissue Eng Part A] Umbilical Cord Blood Transplantation for Children with Thalassemia and Sickle Cell Disease Results suggest that only cord blood units containing an expected infused cell dose greater than 5×107/kg should be considered for transplantation for hemoglobinopathy. [Biol Blood Marrow Transplant] Total Colony Forming Units Are a Strong Independent Predictor of Neutrophil and Platelet Engraftment After Unrelated Umbilical Cord Blood Transplantation: A Single Center Analysis of 435 Cord Blood Transplants CFU dose is a strong independent predictor of engraftment after unrelated umbilical cord blood transplantation and should be used to assess potency when selecting cord blood units for transplantation. [Biol Blood Marrow Transplant] Favorable Outcome of Unrelated Cord Blood Transplantation for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Researchers analyzed the clinical outcomes of 20 Philadelphia chromosome-positive acute lymphoblastic leukemia patients who received unrelated cord blood transplantation (CBT) (n = 8) and unrelated bone marrow transplantation (BMT) (n = 12). The CBT group had significantly better overall survival than the BMT group (P = 0.02). [Biol Blood Marrow Transplant]
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