NK-Cell Education After Allogeneic Transplantation: Dissociation Between Recovery of Cytokine Producing and Cytotoxic Functions Researchers tested the cytokine production and degranulation of reconstituting Natural Killer (NK) cells after adult unrelated donor or umbilical cord blood grafting. [Blood] Successful Mobilization and Engraftment of Peripheral Blood Stem Cells Derived from Donor Cord Blood Cells After a Previous Allogeneic RIC Single Unrelated Cord Blood Transplantation Researchers describe a successful salvage treatment with intensive chemotherapy and stem cell transplantation for a relapse of Hodgkin lymphoma after single umbilical cord blood transplantation with a reduced intensity-conditioning regimen (RIC). [Blood] Hematopoietic Stem Cell Transplantation for CD3δ Deficiency Researchers’ objectives were to study the outcome of CD3δ deficiency by using various modalities of stem cell transplantation. [J Allergy Clin Immunol] Progesterone Promotes Differentiation of Human Cord Blood Fetal T Cells into T Regulatory Cells but Suppresses Their Differentiation into Th17 Cells Researchers report in this work a novel function of progesterone in regulation of naive cord blood fetal T cell differentiation into key T regulatory cell subsets. [J Immunol] Histone Deacetylase Inhibition Enhances Self Renewal and Cardioprotection by Human Cord Blood-Derived CD34+ Cells Results show that histone deacetylase blockade leads to phenotype changes in CD34+ cells with enhanced self renewal and cardioprotection. [PLoS One] Stem-Cell Therapy for Peripheral Arterial Occlusive Disease The aims of this study were to confirm the effectiveness via animal study and safety through clinical trials of using human cord blood-mononuclear cells. [Eur J Vasc Endovasc Surg] |