| PUBLICATIONS (Ranked by Impact Factor of the Journal) | Methionine Aminopeptidase 2 Is Required for Hematopoietic Stem Cell Initiation and Proliferation Researchers investigated the role of methionine aminopeptidase II in hematopoiesis using zebrafish embryo and human umbilical cord blood models. [Blood] Abstract HLA-Targeted Flow Cytometric Sorting of Blood Cells Allows Separation of Pure and Viable Microchimeric Cell Populations Investigators demonstrate applicability of HLA-targeted FACS sorting after pregnancy by separating chimeric maternal cells from child umbilical cord mononuclear cells. [Blood] Abstract Crucial Role of Nuclear Ago2 for hUCB-MSCs Differentiation and Self-Renewal via Stemness Control In this study, researchers demonstrate novel functions and molecular mechanisms of nuclear Argonaute2 (Ago2) in the self-renewal and plasticity of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs). [Antioxid Redox Signal] Abstract Assessment of Neuroprotective Effects of Human Umbilical Cord Blood Mononuclear Cell Subpopulations In Vitro and In Vivo The study suggests that mononuclear cells (MNCs) provide the most prominent neuroprotective effect with CD34+ cells seeming to be particularly involved in the protective action of MNCs. [Cell Transplant] Abstract Predifferentiated Human Committed T-Lymphoid Progenitors Promote Peripheral T-Cell Reconstitution After Stem Cell Transplantation in Immunodeficient Mice Here, researchers analysed the developmental potential of human peripheral blood CD34+ HSCs compared with committed T/NK-lymphoid progenitors from a third-party donor in a murine NOD-scid IL2Rnull model of humanized chimeric haematopoiesis. [Eur J Immunol] Abstract The i Blood Group Antigen as a Marker for Umbilical Cord Blood Derived Mesenchymal Stem Cells Researchers used flow cytometry and mass spectrometric glycan analysis and discovered that linear poly-N-acetyllactosamine structures are expressed in umbilical cord blood derived mesenchymal stem cells, but not in cells differentiated from them. [Stem Cells Dev] Abstract Transcriptional Repression of Mad-Max Complex by Human Umbilical Cord Blood Stem Cells Downregulates ERK in Glioblastoma To study the cell cycle progression and investigate the upstream molecules regulating cyclin D1 expression, researchers analyzed the involvement of ERK and its functionality after treatment with hUCBSC. [Stem Cells Dev] Abstract Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase In this study, scientists screened biologically active natural products for activity to promote expansion of human cord blood (hCB) hematopoietic stem and progenitor cells (HSCs/PCs) ex vivo, and identified Garcinol, a plant-derived histone acetyltransferase inhibitor, as a novel stimulator of hCB HSC/PC expansion. [PLoS One] Abstract Cord Blood CD4+ T Cells Respond to Self Heat Shock Protein 60 (HSP60) Investigators studied whether self-HSP60 reactive T cells are present in cord blood, and if so, what phenotype these cells have. [PLoS One] Abstract Pre-Engraftment Syndrome After Unrelated Donor Umbilical Cord Blood Transplantation in Patients with Hematologic Malignancies Researchers retrospectively analyzed the incidence, risk factors, manifestations, and clinical outcomes of pre-engraftment syndrome in umbilical cord blood transplantation recipients, who had been treated for hematological malignancies at a transplantation center. [Eur J Haematol] Abstract |
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