C/EBPα Is Required for Development of Dendritic Cell Progenitors Investigators report the transcription factor C/EBPα coordinates the development of progenitor cells required for production of multiple categories of dendritic cells (DCs). C/EBPα was needed for differentiation from stem/progenitor cells to common DC progenitors (CDP), but not for transition of CDP to mature DCs. [Blood] Abstract Disease Status and Stem Cell Source Impact on the Results of Reduced Intensity Conditioning Transplant for Hodgkin Lymphoma: A Retrospective Study from the French Society of Bone Marrow Graft Transplantation and Cellular Therapy Researchers retrospectively analyzed 191 patients who underwent reduced intensity allogeneic stem cell transplantation for relapsed or refractory Hodgkin lymphoma and whose data were reported to the French registry. Data suggest that the use of peripheral blood should be preferred whereas umbilical cord blood should be used with caution. [Haematologica] Abstract | Full Article AF-MSCs Fate Can Be Regulated by Culture Conditions In previous studies, the authors isolated and expanded fetal mesenchymal stem cells (MSCs) from second-trimester amniotic fluid (AF) and characterized them based on their phenotype, pluripotency and proteomic profile. In the present study, they investigated the plasticity of these cells based on their differentiation, dedifferentiation and transdifferentiation potential in vitro. [Cell Death Dis] Full Article Novel Single-Cell Functional Analysis of Red Blood Cells Using Laser Tweezers Raman Spectroscopy: Application for Sickle Cell Disease Laser tweezers Raman spectroscopy was used to characterize the oxygenation response of single normal adult, sickle, and cord blood red blood cells to an applied mechanical force. Individual cells were subjected to different forces by varying the laser power of a single-beam optical trap, and the intensities of several oxygenation-specific Raman spectral peaks were monitored to determine the oxygenation state of the cells. [Exp Hematol] Abstract Human Amniotic Fluid Stem Cells Protect Rat Lungs Exposed to Moderate Hyperoxia The authors investigated the role of amniotic fluid stem cells in an adult rat model of hyperoxia lung injury. [Pediatr Pulmonol] Abstract Effects of Connective Tissue Growth Factor on the Regulation of Elastogenesis in Human Umbilical Cord-Derived Mesenchymal Stem Cells Researchers aimed to analyze the connective tissue growth factor effect on elastin production in umbilical cord-derived mesenchymal stem cells and to determine optimal timing of treatment to maximize elastin production. [Ann Plast Surg] Abstract |