Potential of Human Fetal Chorionic Stem Cells for the Treatment of Osteogenesis Imperfecta Scientists showed that intra-peritoneal injection of human fetal chorionic stem cells in murine Osteogenesis Imperfecta neonates reduced fractures, increased bone ductility and bone volume, increased the numbers of hypertrophic chondrocytes, and upregulated endogenous genes involved in endochondral and intramembranous ossification. [Stem Cell Dev] Abstract Amniotic Fluid Stem Cells from EGFP Transgenic Mice Attenuate Hyperoxia-Induced Acute Lung Injury The in vivo therapeutic potential of amniotic fluid stem cells (AFSCs) was evaluated in a model of acute hyperoxia-induced lung injury in mice. The administration of AFSCs significantly reduced the hyperoxia-induced pulmonary inflammation, as reflected by significant reductions in lung wet/dry ratio, neutrophil counts, and the level of apoptosis, as well as reducing the levels of inflammatory cytokine (IL-1β, IL-6, and TNF-α) and early-stage fibrosis in lung tissues. [PLoS One] Full Article Calcium Sensing Receptor Expression in Ovine Amniotic Fluid Mesenchymal Stem Cells and the Potential Role of R-568 during Osteogenic Differentiation Researchers investigated the presence of Calcium Sensing Receptor (CaSR) in ovine Amniotic Fluid Mesenchymal Stem Cells (oAFMSCs) and then the potential role of calcimimetics in in vitro osteogenesis. oAFMSCs were isolated, characterized and analyzed to examine the possible presence of CaSR by western blotting and flow cytometry analysis. [PLoS One] Full Article Higher Therapeutic CsA Levels Early Post Transplantation Reduces Risk of Acute GVHD and Improves Survival Scientists studied whether early CsA trough levels were associated with the risk of acute GVHD in 337 patients after either sibling PBSC or double umbilical cord blood transplantation. [Bone Marrow Transplant] Abstract Sauchinone from Saururus chinensis Protects Vascular Inflammation by Heme Oxygenase-1 Induction in Human Umbilical Vein Endothelial Cells Researchers investigated the effect of sauchinone in suppressing cell adhesion molecules such as vascular cell adhesion molecule-1 and intracellular adhesion molecule-1 expression in high glucose stimulated human umbilical vein endothelial cells. [Phytomedicine] Abstract Clinical Outcomes of Allogeneic Stem Cell Transplantation for Relapsed or Refractory Follicular Lymphoma: A Retrospective Analysis by the Fukuoka Blood and Marrow Transplantation Group Researchers retrospectively analyzed the outcome of allogeneic hematopoietic stem cell transplantation in 30 patients with follicular lymphoma. There were no significant differences in the estimated 2-year overall survival rate between patients who received myeloablative conditioning and those who received reduced-intensity conditioning, and among the recipients of related bone marrow (BM)/peripheral blood stem cell, unrelated BM and umbilical cord blood. [Int J Hematol] Abstract Human Umbilical Cord-Derived MSC Culture: The Replacement of Animal Sera with Human Cord Blood Plasma In order to make the best of umbilical cord blood, human umbilical cord blood plasma was dialyzed to replace fetal bovine serum in culture medium. Human umbilical cord-derived mesenchymal stem cells (MSCs) were cultured in the new medium. [In Vitro Cell Dev Biol Anim] Abstract |