Transplantation of Cryopreserved Human Umbilical Cord Blood Mononuclear Cells Does Not Induce Sustained Recovery after Experimental Stroke in Spontaneously Hypertensive Rats Researchers investigated the neurorestorative potential of cryopreserved human umbilical cord blood mononuclear cells after permanent middle cerebral artery occlusion in spontaneously hypertensive rats. [J Cereb Blood Flow Metab] Abstract Contralateral Extremities Benefit from Locally Administered Bone Marrow-Derived Mononuclear Cells and Cord Blood Serum in Diabetic Ischemic Wound Healing Impaired wound healing could be a disaster especially in diabetes and amputation is the major risk. Investigators evaluated the benefit of bone marrow-derived mononuclear cells and cord blood serum on wound healing. [Stem Cell Rev Rep] Abstract Human Umbilical Cord Blood-Derived CD34 Positive Endothelial Progenitor Cells Stimulate Osteoblastic Differentiation of Cultured Human Periosteal-Derived Osteoblasts Investigators examined the effects of human umbilical cord blood-derived CD34 positive endothelial progenitor cells on osteoblastic differentiation of cultured human periosteal-derived osteoblasts. [Tissue Eng Part A] Abstract Transplantation of Umbilical Cord-Derived Mesenchymal Stem Cells into the Striata of R6/2 Mice: Behavioral and Neuropathological Analysis Mesenchymal stem cells, isolated from the umbilical cord of day 15 gestation pups, were transplanted intrastriatally into 5-week-old R6/2 mice at either a low-passage or high-passage. Mice were tested behaviorally for 6 weeks using the rotarod task, the Morris water maze, and the limb-clasping response. [Stem Cell Res Ther] Abstract | Full Article Conditioned Medium as a Strategy for Human Stem Cells Chondrogenic Differentiation The authors aimed to achieve chondrogenic differentiation of two different sources of stem cells using conditioned medium, without adding growth factors. They tested both human bone marrow-derived mesenchymal stem cells and human Wharton’s jelly-derived stem cells. [Tissue Eng Regen Med] Abstract Cotransplantation of Human Umbilical Cord-Derived Mesenchymal Stem Cells and Umbilical Cord Blood-Derived CD34+ Cells in a Rabbit Model of Myocardial Infarction Scientists investigated the effect of hypoxic preconditioning on the immunomodulatory properties of human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) and the effect of cotransplantation of hUC-MSCs and human umbilical cord blood-derived CD34+ cells in a rabbit model of myocardial infarction. [Mol Cell Biochem] Abstract Neuronal Cell Differentiation of Mesenchymal Stem Cells Originating from Canine Amniotic Fluid Researchers investigated whether canine amniotic-fluid-derived mesenchymal stem cells can differentiate into neural precursor cells in vitro when exposed to neural induction reagent. [Hum Cell] Full Article |