Antiretroviral-Free HIV-1 Remission and Viral Rebound after Allogeneic Stem Cell Transplantation: Report of Two Cases Researchers characterized HIV-1 reservoirs in blood and tissues and perform analytic antiretroviral treatment interruptions to determine the potential for allogeneic hematopoietic stem cell transplantation to lead to sustained, antiretroviral-free HIV-1 remission. [Ann Intern Med] Abstract Calcium Sensing Receptor Activation by Calcimimetic R-568 in Human Amniotic Fluid Mesenchymal Stem Cells: Correlation with Osteogenic Differentiation Using western blotting, immunofluorescence and flow cytometry, investigators consistently observed constitutive calcium sensing receptor in osteo-differentiating mesenchymal stem cells derived from human amniotic fluid. [Stem Cells Dev] Abstract Dissection of the Cord Blood Stromal Component Reveals Predictive Parameters for Culture Outcome Researchers present their nine-year experience for the consistent isolation of cord blood (CB)-derived multipotent mesenchymal stromal cells (MSCs). Even though nearly one CB unit out of two retains the potential to give rise to MSC colonies, only 46% of them can be cultured till low passages, but one fourth of those reaches even higher passages. [Stem Cells Dev] Abstract HUCBCs Increase Angiopoietin 1 and Induce Neurorestorative Effects after Stroke in T1DM Rats Scientists investigated the neurorestorative effects and underlying mechanisms of stroke treatment with human umbilical cord blood cells (HUCBCs) in type one diabetes mellitus (T1DM) rats [CNS Neurosci Ther] Abstract Older Patients with Myeloma Derive Similar Benefit from Autologous Transplantation Investigators analyzed 11,430 autologous hematopoietic cell transplant (AHCT) recipients for plasma cell myeloma prospectively reported to the CIBMTR between 2008 and 2011 representing the majority of US AHCT activity during this period. [Biol Blood Marrow Transplant] Abstract Differentiation of Human Umbilical Cord Mesenchymal Stem Cells into Prostate-Like Epithelial Cells In Vivo Researchers report that when human umbilical cord mesenchymal stem cells were combined with rat urogenital sinus stromal cells and transplanted into the renal capsule in vivo, they could differentiate into prostate epithelial-like cells that could be verified by prostate epithelial cell-specific markers including the prostate specific antigen. [PLoS One] Full Article Effects of Interruptions of Controlled-Rate Freezing on the Viability of Umbilical Cord Blood Stem Cells Cord blood cells were stored in liquid nitrogen vapor phase for 127 ± 48.1 hours before postthaw recovery, viability, and survival of total nucleated cells and/or CD45+ cells, CD34+ cells, and colony-forming unit-granulocyte-macrophage were assessed. [Transfusion] Abstract |