Low Intensity Lympho-Ablative Regimen followed by Autologous Hematopoietic Stem Cell Transplantation in Severe Forms of Multiple Sclerosis: A MRI-Based Clinical Study Researchers report magnetic resonance imaging (MRI) and clinical data in a small cohort of patients treated with a low-intensity lympho-ablative regimen, followed by autologous hematopoietic stem cell transplantation. [Mult Scler] Abstract Absolute Lymphocyte Count as Predictor of Overall Survival for Patients with Multiple Myeloma Treated with Single Autologous Stem Cell Transplant To assess whether absolute lymphocyte count (ALC) recovery has prognostic significance in patients with MM undergoing single autologous stem cell transplant (ASCT), researchers conducted a retrospective analysis of ALC at different time-points in patients with MM. [Leuk Lymphoma] Abstract High-Dose Chemotherapy with Full BEAM followed by Autologous Stem Cell Transplantation Is an Effective Treatment for Elderly Patients with Poor-Prognosis Lymphoma Scientists present a retrospective analysis of 73 consecutive patients aged over 65 years treated for aggressive or relapsed lymphoma by high-dose chemotherapy with BEAM at full dosage followed by autologous stem cell transplantation. [Leuk Lymphoma] Abstract Haploidentical Stem Cell Transplantation Augmented by CD45RA Negative Lymphocytes Provides Rapid Engraftment and Excellent Tolerability Eight children with relapsed or refractory solid tumors were transplanted following myeloablative conditioning. Each patient received two cell products, one created by CD3 depletion and the other through CD45RA depletion. [Pediatr Blood Cancer] Abstract Prolonged Clinical Remissions in Patients with Relapsed or Refractory Follicular Lymphoma Treated with Autologous Stem Cell Transplantation Incorporating Rituximab Three sequential Phase II trials were conducted with different immunotherapy approaches to enhance the outcome of autologous transplant (high-dose therapy and autologous stem cell transplantation) for recurrent follicular lymphoma. [Ann Hematol] Abstract The Effect of Extended Passaging on the Phenotype and Osteogenic Potential of Human Umbilical Cord Mesenchymal Stem Cells Investigators aimed to assess morphology, viability, mesenchymal stem cell (MSC) marker expression, and osteogenic activity of human umbilical cord MSCs after extended passaging. [Mol Cell Biochem] Abstract Extracellular Regulated Protein Kinases 1/2 Phosphorylation Is Required for Hepatic Differentiation of Human Umbilical Cord-Derived Mesenchymal Stem Cells Scientists investigated the signals involved in the hepatic differentiation of human umbilical cord-derived mesenchymal stem cells (hUCMSCs). hUCMSCs were treated with mouse fetal liver-conditioned medium to induce hepatic differentiation. [Exp Biol Med] Abstract Effect of Genetic Polymorphism of Cyp3A5 and Cyp2C19, and Concomitant Use of Voriconazole on Blood Tacrolimus Concentration in Patients Receiving Hematopoietic Stem Cell Transplantation This study is a single-institute, prospective study including 21 adult patients who underwent hematopoietic stem cell transplantation and received 24 hour continuous intravenous administration of tacrolimus at Mie University Hospital. [Ther Drug Monit] Abstract |