The Effects of Secretion Factors from Umbilical Cord Derived Mesenchymal Stem Cells on Osteogenic Differentiation of Mesenchymal Stem Cells Researchers investigated the effects of secretion factors of human umbilical cord derived mesenchymal stem cells (MSCs) on osteogenesis of human bone marrow derived MSCs. [PLoS One] Full Article Microvesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Facilitate Tubular Epithelial Cell Dedifferentiation and Growth via Hepatocyte Growth Factor Induction In a rat model of unilateral acute kidney injury, the administration of mesenchymal stem cell-derived microvesicles promoted kidney recovery. One of the mechanisms of action is the acceleration of tubular cell dedifferentiation and growth. [PLoS One] Full Article Impact of Length of Cryopreservation and Origin of Cord Blood Units on Hematologic Recovery following Cord Blood Transplantation To determine whether long-term cryopreservation and international shipment of cord blood units (CBUs) affect the quality of the units and outcome after transplantation, scientists retrospectively analyzed the quality of 95 CBUs and the hematologic recovery of 127 patients with hematological malignancy following single-unit cord blood transplantation. [Bone Marrow Transplant] Abstract Human Allogeneic AB0/Rh-Identical Umbilical Cord Blood Cells in the Treatment of Juvenile Patients with Cerebral Palsy During a post-registration clinical investigation, the safety and efficacy of intravenous infusion of allogeneic human leukocyte antigen-unmatched umbilical cord blood cells were studied in 80 pediatric patients with cerebral palsy and associated neurological complications. [Cytotherapy] Abstract Human Umbilical Cord Blood Cells Ameliorate Motor Deficits in Rabbits in a Cerebral Palsy Model Scientists tested human umbilical cord blood cell therapy in a validated rabbit model of cerebral palsy after acute changes secondary to hypoxic-ischemic injury had subsided. [Dev Neurosci] Abstract Enhanced Endothelial Progenitor Cell Mobilization and Function through Direct Manipulation of Hypoxia Inducible Factor-1α Researchers investigated the effects of directly manipulating hypoxia-inducible factor-1α on human endothelial progenitor cells (EPCs) in vitro. EPCs were isolated from human umbilical cord blood. [Cell Biochem Funct] Abstract Therapeutic Potential of Human Umbilical Cord Blood Mesenchymal Stem Cells on Erectile Function in Rats with Cavernous Nerve Injury Investigators evaluated the therapeutic potential of human umbilical cord blood mesenchymal stem cells on promoting erectile function in a rat model of bilateral cavernous nerve crush injury. [Biotechnol Lett] Abstract |