Molecular and Phenotypic Characterization of CD133 and SSEA4 Enriched Very Small Embryonic-Like Stem Cells in Human Cord Blood Researchers describe enrichment strategy and molecular and phenotypic characterization of human cord blood embryonic-like stem cells (VSELs). Flow cytometry analysis revealed that majority of VSELs were present in the red blood cells pellet after Ficoll-Hypaque centrifugation in contrast to the hematopoietic stem cells in the interphase layer. [Leukemia] Abstract Hair Regrowth in Alopecia Areata Patients following Stem Cell Educator Therapy Scientists developed a stem cell educator therapy in which a patient’s blood is circulated through a closed-loop system that separates mononuclear cells from the whole blood, allowing the cells to briefly interact with adherent human cord blood-derived multipotent stem cells, and returning the “educated” autologous cells to the patient’s circulation. [BMC Med] Abstract | Full Article Proteomic Analysis of Porcine Mesenchymal Stem Cells Derived from Bone Marrow and Umbilical Cord: Implication of the Proteins Involved in the Higher Migration Capability of Bone Marrow Mesenchymal Stem Cells Porcine bone marrow mesenchymal stem cells (MSCs) and umbilical cord MSCs were evaluated with flow cytometric and adipogenic and osteogenic differentiation analyses. [Stem Cell Res Ther] Abstract | Full Article Umbilical Cord Mesenchymal Stem Cells Modulate Dextran Sulphate Sodium Induced Acute Colitis in Immunodeficient Mice Scientists examined the protective potential of exogenously administered human umbilical cord derived mesenchymal stem cells against dextran sulphate sodium induced acute colitis in immunodeficient NOD.CB17-Prkdc scid/J mice with particular attention to endoplasmic reticulum stress. [Stem Cell Res Ther] Abstract | Full Article Role of Hepatocyte Growth Factor in the Immunomodulation Potential of Amniotic Fluid Stem Cells Researchers found that hepatocyte growth factor produced by human amniotic fluid stem cells exerts a cytoprotective role, inducing an increase in caspase-dependent apoptosis in human immune cells. [Stem Cells Transl Med] Abstract Human Umbilical Cord-Derived Mesenchymal Stem Cells Improve Learning and Memory Function in Hypoxic-Ischemic Brain-Damaged Rats via an IL-8-Mediated Secretion Mechanism Rather than Differentiation Pattern Induction Based on flow cytometry analysis, human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) exhibited the morphological characteristics and surface markers of MSCs. All types of hUC-MSCs, including differentiated and redifferentiated cells, promoted learning and memory function recovery in hypoxic-ischemic brain damaged rats. [Cell Physiol Biochem] Full Article GFP Labeling and Hepatic Differentiation Potential of Human Placenta-Derived Mesenchymal Stem Cells Scientists established human placenta-derived mesenchymal stem cells (hPMSCs) expressing green fluorescent protein and assayed their hepatic functional differentiation in vitro. The green fluorescent protein (GFP) gene was transduced into hPMSCs using a lentivirus to establish GFP+ hPMSCs. [Cell Physiol Biochem] Full Article Characteristics of Human Amniotic Fluid Mesenchymal Stem Cells and Their Tropism to Human Ovarian Cancer Investigators obtained and characterized human amniotic fluid mesenchymal stem cells (AFMSCs) and detected their ovarian cancer tropsim in nude mice model. AFMSCs presented a fibroblastic-like morphology during the culture. [PLoS One] Full Article Efficacy and Safety of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Anterior Cruciate Ligament Reconstruction of a Rabbit Model: New Strategy to Enhance Tendon Graft Healing Researchers investigated whether non-autologous transplantation of human umbilical cord blood-derived mesenchymal stem cells could be integrated safely at the bone-tendon junction without immune rejection and could enhance bone-tendon healing effectively during anterior cruciate ligament reconstruction in an animal model. [Arthroscopy] Abstract |