Polymorphism in TGFB1 Is Associated with Worse Non-Relapse Mortality and Overall Survival after Stem Cell Transplantation with Unrelated Donors The authors sequenced TGFB1 regulatory region and assigned allelic genotypes in a large cohort of hematopoietic stem cell transplantation patients and donors. They analyzed 522 unrelated donor-patient pairs and examined the combined effect of all the common polymorphisms in this genomic region. [Haematologica] Abstract | Full Article Time-Dependent Effects of Clinical Predictors in Unrelated Hematopoietic Stem Cell Transplantation Scientists present a systematic analysis and description of selected clinical predictors influencing the outcome of hematopoietic stem cell transplantation in a time-dependent manner based on a registry data analysis from the German Registry for Stem Cell Transplantation. [Haematologica] Abstract | Full Article Long-Term Outcomes of Fludarabine, Melphalan and Antithymocyte Globulin as Reduced-Intensity Conditioning Regimen for Allogeneic Hematopoietic Stem Cell Transplantation in Children with Primary Immunodeficiency Disorders: A Prospective Single Center Study Forty-five children affected by primary immunodeficiency disorders with a median age of 21 months underwent allogeneic hematopoietic stem cell transplantation in the researchers’ institute from 2007 to 2013. All patients received an identical reduced-intensity conditioning regimen. [Bone Marrow Transplant] Abstract Effect of Immune Modulation in Relapsed Peripheral T-Cell Lymphomas after Post-Allogeneic Stem Cell Transplantation: A Study by the Societe Francaise De Greffe De Moelle Et De Therapie Cellulaire (SFGM-TC) Peripheral T-cell lymphoma carries a poor prognosis. To document a possible graft-versus-lymphoma effect in this setting, investigators evaluated the impact of immunomodulation in 63 patients with peripheral T-cell lymphoma who relapsed after allogeneic transplant in 27 SFGM-TC centers. [Bone Marrow Transplant] Abstract Comparison of Biological Characteristics of Mesenchymal Stem Cells Derived from Maternal-Origin Placenta and Wharton’s Jelly Investigators compared mesenchymal stem cells derived from Wharton’s jelly in the umbilical cord with those derived from the decidual basalis in the maternal part of the placenta to better understand the similarities and differences between these two cell types. [Stem Cell Res Ther] Full Article Interaction of Natural Killer Cells with Neutrophils Exerts a Significant Antitumor Immunity in Hematopoietic Stem Cell Transplantation Recipients Researchers examined whether natural killer cells exert an antitumor effect after syngeneic hematopoietic stem cell transplantation in a murine colon cancer model. [Cancer Med] Full Article BDNF-Hypersecreting Human Umbilical Cord Blood Mesenchymal Stem Cells Promote Erectile Function in a Rat Model of Cavernous Nerve Electrocautery Injury Investigators hypothesized that intracavernous injection of BDNF-hypersecreting human umbilical cord blood mesenchymal stem cells can ameliorate erectile dysfunction in a rat model of cavernous nerve electrocautery injury. [Int Urol Nephrol] Abstract |