Cord Blood News Volume 8.08 | Mar 3 2016

Comparison of Transplant Outcomes from Matched Sibling Bone Marrow or Peripheral Blood Stem Cell and Unrelated Cord Blood in Patients 50 Years or Older
The authors retrospectively analyzed Japanese registration data of 2,091 patients with acute myeloid leukemia, acute lymphoblastic leukemia, and myelodysplastic syndrome aged 50 years or older who underwent matched sibling donors (MSD) bone marrow transplantation, MSD peripheral blood stem cell transplantation, or unrelated cord blood transplantation. [Am J Hematol] Abstract

Equine Amniotic Microvesicles and Their Anti-Inflammatory Potential in a Tenocyte Model In Vitro
The presence and type of microvesicles (MVs) secreted by amniotic mesenchymal cells was investigated and the response of equine tendon cells to MVs was studied using a dose-response curve at different concentrations and different times. [Stem Cells Dev] Abstract

Human Amniotic Mesenchymal Stem Cells Alleviate Lung Injury Induced by Ischemia and Reperfusion after Cardiopulmonary Bypass in Dogs
Investigators assessed the capacity of human amniotic MSCs to ameliorate ischemia/reperfusion injury in a dog model of cardiopulmonary bypass. [Lab Invest] Abstract

Frequency and Risk Factors Associated with Cord Graft Failure (CGF) after Transplant with Single Unit Umbilical Cord Cells Supplemented by Haploidentical Cells (Haplo-Cord) with Reduced-Intensity Conditioning
Scientists described the frequency, complications and risk factors of CGF following reduced-intensity conditioning haplo-cord hematopoietic stem cell transplantation. [Biol Blood Marrow Transplant] Article

Comparative Analysis of MicroRNA Expression in Human Mesenchymal Stem Cells from Umbilical Cord and Cord Blood
Investigators found that microRNAs significantly repressed insulin signaling in cord blood mesenchymal stem cells (CBMSCs), while neuronal related processes were more repressed in CBMSCs. [Genomics] Abstract

Isolation and Culture of Embryonic Stem Cells, Mesenchymal Stem Cells, and Dendritic Cells from Humans and Mice
Researchers described the methods of isolating and culturing various types of stem cells, like human embryonic stem cells, human umbilical cord derived mesenchymal stem cells, murine bone marrow derived mesenchymal stem cells, murine adipose tissue derived mesenchymal stem cells, and murine bone marrow derived dendritic cells. [Methods Mol Biol] Full Article

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Creative Medical Health Inc. Announces Creation of AngioStem Inc. Subsidiary to Commercialize Issued Cardiovascular Stem Cell Patent
Creative Medical Health announced formation of a subsidiary company, AngioStem Inc., dedicated to commercialization of its cardiovascular assets, including issued US patent #9,205,112, titled “Combination Therapy of Cardiovascular Disease.” The patent covers the use of autologous and allogeneic adult stem cells such as cord blood and mesenchymal stem cells in combination with modulation of oxidative stress in treatment of heart failure. [Creative Medical Health (Business Wire)] Press Release

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Research Fellow – Erythropoiesis (New York Blood Center)

Research Technician I – Umbilical Cord Blood (Fred Hutchinson Cancer Research Center)

Postdoctoral Fellow – Stem Cell Biology and Regenerative Medicine (Cleveland Clinic)

Translational Research Scientist – Hematology/Oncology (University of Chicago)

Postdoctoral Associate – Epigenetic Regulation of Normal and Leukemic Stem Cells (Sanford Burnham Prebys Medical Discovery Institute)

Postdoctoral Positions – Immunology, Cancer, and Stem Cells (University of Connecticut)

PhD Position – Stem Cells and Transplantation (University of Geneva)

Postdoctoral position – Regenerative Medicine (University of Copenhagen)

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