Both High and Low Levels of Cellular Epstein-Barr Virus DNA in Blood Identify Failure after Hematologic Stem Cell Transplantation in Conjunction with Acute GVHD and Type of Conditioning The authors evaluated the impact of EBV load on survival of 51 patients, who had received hematopoietic stem cell transplantation patients for different types of malignancies or non-malignancies. Different sources of stem-cells (peripheral blood stem, bone marrow, or umbilical cord blood) were used. [Oncotarget] Full Article Chaotic Time Series Prediction for Prenatal Exposure to Polychlorinated Biphenyls in Umbilical Cord Blood Using the Least Squares SEATR Model Investigators studied prenatal exposure to polychlorinated biphenyls by chaotic time series prediction using the least squares self-exciting threshold autoregressive (SEATR) model in umbilical cord blood in an electronic waste contaminated area. [Sci Rep] Full Article Equine Mesenchymal Stromal Cells (MSC) from Different Sources Efficiently Differentiate into Hepatocyte Like Cells (HLC) Researchers differentiated equine umbilical cord blood (UCB)-derived MSC into HLC and found that these cells exhibited a distinct polygonal morphology, stored glycogen as visualized by periodic acid Schiff’s reagent staining, and were positive for albumin and other hepatocyte-specific genes. They demonstrated that UCB-HLC could be revived following cryopreservation and retained their phenotype for at least ten days. [Tissue Eng Part C Methods] Abstract The Differentiation of Amniotic Fluid Stem Cells into Sweat Gland-Like Cells Is Enhanced by the Presence of Shh in the Conditioned Medium Researchers induced CD117+ human amniotic fluid stem cells to differentiate into sweat gland-like cells based on use of conditioned medium from the human sweat gland cells. [Exp Dermatol] Abstract Stiffness-Controlled Three-Dimensional Collagen Scaffolds for Differentiation of Human Wharton’s Jelly Mesenchymal Stem Cells into Cardiac Progenitor Cells Investigators developed stiffness-controlled collagen scaffolds to allow proliferation and differentiation of mesenchymal stem cell into cardiac progenitor cells. Transforming growth factor β2, was used to induce stem cell differentiation into cardiac lineage cells. [J Biomed Mater Res A] Abstract Immunoregulatory Function of Neonatal Nucleated Red Blood Cells in Humans Investigators found that human cord blood nucleated red blood cells have a regulatory function in the innate immune reaction. These cells suppressed the production of inflammatory cytokines including TNF-α and IL-1β from monocytes in response to lipopolysaccharide. [Immunobiology] Abstract |