 | | Vol. 7.00 – 4 January, 2021 |
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| A nanocomposite scaffold was developed for in-situ therapy after melanoma surgery as well as wound healing, which was fabricated by embedding photothermal-capable black phosphorus nanosheets into bioresorbable Gelatin-PCL nanofibrous scaffold.
[Biomaterials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
| | The authors demonstrated both safeties of transplantation of a cultured human autologous dermal fibroblast sheet to lung air leaks.
[npj Regenerative Medicine] |
| | Investigators analyzed whether changes in DNA 5-hydroxymethylation were an element of age-related epigenetic drift. They tested primary fibroblast cultures originating from individuals aged 22–35 years and 74–94 years.
[International Journal of Molecular Sciences] |
| | Scientists investigated the effects of electromagnetic fields with long-term evolution and 5G bandwidth on skin pigmentation in vitro.
[International Journal of Molecular Sciences] |
| | Using a cultured keratinocyte model system, investigators showed that depletion of α-catenin perturbed adherens junctions, enhanced cell proliferation and motility, and decreased dependence on exogenous growth factors.
[Molecular Biology of the Cell] |
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| Researchers generated conditional knockout mice in which the High-mobility group box 1 protein (HMGB1) gene was specifically deleted in keratinocytes, and examined its role in allergic contact dermatitis models.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| To investigate the mechanism of oncogenic tolerance, the authors induced HrasG12V in single murine epidermal cells and followed them long-term.
[eLife] |
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| Researchers showed that CD147 was translocated from the cell membrane to the mitochondria in advanced melanoma. Melanoma patients with CD147 localized to the mitochondria conferred a worse prognosis.
[International Journal of Biological Sciences] |
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| Exome sequencing data of cancer patients and analysis of distinct melanoma and bladder cancer cell lines suggested differences in cancer cell-exposed glycocalyx components such as heparan sulfate. Scientists indicated that glycocalyx differences affected the binding of cationic chitosan nanocapsules.
[Scientific Reports] |
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| Investigators review the clinical presentations of cutaneous immune‐related adverse effects associated with checkpoint inhibitor therapy in adult patients with metastatic malignant melanoma.
[British Journal of Dermatology] |
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| Advances in the development of multifunctional hydrogel-based dressings for wound healing are highlighted.
[International Journal of Biological Macromolecules] |
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| The authors review the functions and mechanisms of Tβ4 in hair follicle (HF) growth and development and describe the endogenous and exogenous actions of Tβ4 in HFs to provide insights into the roles of Tβ4 in HF growth and development.
[Journal of Cellular and Molecular Medicine] |
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| Verrica Pharmaceuticals, Inc. announced that it has resubmitted the New Drug Application (NDA) for VP-102 for the treatment of molluscum contagiosum to the FDA. The NDA for VP-102 was resubmitted based on the outcome and final minutes of a Type A meeting with the FDA, which was conducted to obtain clarity on the Complete Response Letter issued by the FDA in July 2020.
[Verrica Pharmaceuticals, Inc.] |
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| January 7 – 8, 2021
Virtual |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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| | University of Copenhagen – Copenhagen, Denmark |
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| | University of Cincinnati – Cincinnati, Ohio, United States |
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| | Columbia University Medical Center – New York, New York, United States |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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