Dermal Cell News Volume 7.12 | Apr 5 2021

    By
    Justin.choi
    -
    0
    51







    2021-04-05| DCN 7.12


    Dermal Cell News by STEMCELL Technologies
    Vol. 7.12 – 5 April, 2021
    TOP STORY

    Corticosterone Inhibits GAS6 to Govern Hair Follicle Stem-Cell Quiescence

    Scientists showed that under chronic stress, increased levels of corticosterone prolong hair follicle stem cell quiescence and maintain hair follicles in an extended resting phase.
    [Nature]

    Abstract Press Release
    CloneR for Enhancing the Cloning Efficiency and Single-Cell Survival of hPSCs
    PUBLICATIONSRanked by the impact factor of the journal

    Bacteria Induce Skin Regeneration via IL-1β Signaling

    Scientists assessed the function of skin bacteria in wound healing and wound-induced hair follicle neogenesis (WIHN), a rare adult organogenesis model.
    [Cell Host & Microbe]

    AbstractGraphical Abstract

    Streptococcus pyogenes Upregulates Arginine Catabolism to Exert Its Pathogenesis on the Skin Surface

    Researchers showed that arginine was a nutrient source that promoted the pathogenicity of S. pyogenes on the skin.
    [Cell Reports]

    Full Article

    Human Skin Aging is Associated with Increased Expression of the Histone Variant H2A.J in the Epidermis

    Scientists investigated histone variant H2A.J as a new biomarker to detect senescent cells during human skin aging.
    [npj Aging and Mechanisms of Disease]

    Full Article

    Amplify Antimicrobial Photo Dynamic Therapy Efficacy with Poly-Beta-Amino Esters (PBAEs)

    Researchers reported for the first time the possibility of harvesting the cell penetrating properties of poly-beta-amino esters in combination with toluidine blue O to shorten antimicrobial photo dynamic therapy exposure time.
    [Scientific Reports]

    Full Article

    Transcriptome Analysis of Human Dermal Fibroblasts Following Red Light Phototherapy

    Scientists reported that red light may improve skin fibrosis via photobiomodulation, the process by which photosensitive chromophores in cells absorb visible or near-infrared light and undergo photophysical reactions.
    [Scientific Reports]

    Full Article

    Exopolysaccharide from Lactobacillus plantarum HY7714 Protects against Skin Aging through Skin-Gut Axis Communication

    Investigators studied the role of exopolysaccharides produced by lactic acid bacteria identified as Lactobacillus plantarum HY7714 in regulating tight junctions in intestinal epithelial cells and increasing moisture retention in human dermal fibroblasts cells.
    [Molecules]

    Full Article

    PPP6C Negatively Regulates Oncogenic ERK Signaling through Dephosphorylation of MEK

    The authors identified PPP6C, a phosphatase frequently mutated or downregulated in melanoma, as a major MEK phosphatase in cells exhibiting oncogenic ERK pathway activation.
    [Cell Reports]

    Full ArticleGraphical Abstract

    CYP27A1-Dependent Anti-Melanoma Activity of Limonoid Natural Products Targets Mitochondrial Metabolism

    Scientists suggested a strategy for melanoma-specific targeting by exploiting the expression of MITF target gene CYP27A1 and inhibiting mitochondrial oxidative phosphorylation in BRAF mutant melanomas.
    [Cell Chemical Biology]

    AbstractGraphical Abstract
    Explore scientific events this April with the Science Events Calendar.
    REVIEWS

    A Cross-Species Analysis of Systemic Mediators of Repair and Complex Tissue Regeneration

    The authors explore the ways in which systemic cues and circulating factors affect the initiation of regeneration, the regenerative process, and its outcome.
    [NPJ Regenerative Medicine]

    Full Article

    Current Standards and Pitfalls Associated with the Transfection of Primary Fibroblast Cells

    Scientists describe critical points that should be considered when selecting a method for transfecting fibroblasts.
    [Biotechnology Progress]

    Abstract
    INDUSTRY AND POLICY NEWS

    Pinnacle Dermatology, a Chicago Pacific Founders Portfolio Company, Acquires Ariano Dermatology in Naperville, IL

    Pinnacle Dermatology, a Chicago Pacific Founders portfolio company, has acquired Ariano Dermatology, led by Dr. Moira Ariano, in Naperville, IL.
    [Pinnacle Dermatology (GlobeNewswire)]

    Press Release

    Biofrontera Submits Application for FDA Approval of New BF-RhodoLED® XL Lamp

    Biofrontera AG announced the submission for approval of a new, significantly larger red-light source for photodynamic therapy to be used in combination with Ameluz®, the BF-RhodoLED® XL, to the US Food and Drug Administration.
    [Biofrontera AG (GlobeNewswire)]

    Press Release
    FEATURED EVENT

    ISSCR: Stem Cells – From Basic Science to Clinical Translation

    October 27 – 29, 2021
    Tokyo, Japan

    > See All Events

    JOB OPPORTUNITIES

    Research Specialist – Skin Stem Cells

    Howard Hughes Medical Institute – New York, New York, United States

    Medicinal Chemist – Muscle-Wasting, Neurodegeneration, and Oncology

    Almac – Belfast, Ireland

    Associate Researcher – Developmental and Regenerative Biology

    Mount Sinai Health System – New York, New York, United States

    Postdoctoral Fellow – Diet and Melanoma

    MD Anderson Cancer Center – Houston, Texas, United States

    Postdoctoral Fellow – Signaling Pathways and Melanoma

    The Wistar Institute – Philadelphia, Pennsylvania, United States

    > See All Jobs

    Submit an article, publication, job or event
    Brought to you by
    stemcell-logo-for newsletter-2
    Dermal Cell News Twitter